SPECIAL ARTICLE

Facing internet fake-medicine and web para-pharmacy in the total absence of official recommendations from medical societies   

Davide Mauri, Lampriani Tsali, Nikolaos P.Polyzos, Antonis Valachis, Georgia Zafeiria, Konstantina Kalopita, Anna Tsiara, Melina Yerolatsite, Georgios Zarkavelis, Eleftherios Kampletsas, Ioanna Mouzaki, Panagiotis Ntellas, Panagiotis Filis, Georgios Pentheroudakis; pp 1314-1325 (Pubmed Abstract, PDF)

REVIEW ARTICLES

Acute myeloid leukaemia: recent data on prognostic gene mutations, in relation to stratified therapies for elderly patients

Emmanouela Niki Soura, George Albert Karikas; pp 1326-1339 (Pubmed Abstract, PDF)

Current and emerging first-line systemic therapies in metastatic clear-cell renal cell carcinoma

Theodoros Tegos, Konstantinos Tegos, Areti Dimitriadou, Georgios Dimitriadis; pp 1340-1353 (Pubmed Abstract, PDF)

Irreversible electroporation and sarcomas: where do we stand?

Michail Vailas, Athanasios Syllaios, Natasha Hashemaki, Maria Sotiropoulou, Dimitrios Schizas, Alexandros Papalampros, Evangelos Felekouras, Emmanouel Pikoulis; pp 1354-1359 (Pubmed Abstract, PDF)

Role of the contrast-enhanced spectral mammography for the diagnosis of breast metastases from extramammary neoplasms

Daniele La Forgia, Annamaria Catino, Rosalba Dentamaro, Domenico Galetta, Gianluca Gatta, Liliana Losurdo, Raffaella Massafra, Anna Scattone, Sabina Tangaro, Annarita Fanizzi; pp 1360-1366 (Pubmed Abstract, PDF)

COMMENTARY

Expanding treatment options for resectable gastric cancer: Is it a countdown for radiotherapy?

Mutlu Hizal, Mehmet AN. Sendur, Burak Bilgin, Muhammed Bulent Akinci,Didem Sener Dede, Bulent Yalcin; pp 1367-1370 (Pubmed Abstract, PDF)

ORIGINAL ARTICLES

LIVER CANCER

Associating liver partition and portal vein ligation for staged hepatectomy in patients with primary liver malignancies: A systematic review of the literature

Efstratia Baili, Diamantis I. Tsilimigras, Dimitrios Filippou, Agis Ioannidis, Anargyros Bakopoulos, Nikolaos Machairas, Alexandros Papalampros, Athanasios Petrou, Demetrios Moris; pp 1371-1381 (Pubmed Abstract, PDF)

Hepatectomy combined with sorafenib in patients with intermediate-advanced hepatocellullar carcinoma

Hongfei Zhu, Bogen Ye, Zhenguo Qiao, Li Zeng, Qigen Li; pp 1382-1389 (Pubmed Abstract, PDF)

Surgery versus external beam radiation therapy for AJCC stage I hepatocellular carcinoma

Bing Han, Lichun Shao, Chuan Li, Ying Xu, Yufu Tang, Lei Han, Xingshun Qi; 1390-1401 (Pubmed Abstract, PDF)

Clinical efficacy analysis of transcatheter arterial chemoembolization (TACE) combined with radiofrequency ablation (RFA) in primary liver cancer and recurrent liver cancer

Yu Sun, Shangwei Ji, Hong Ji, Lin Liu, Chunsheng Li; pp 1402-1407 (Pubmed Abstract, PDF)

Aberrant expression of CD13 and stem cell markers in CD133induced liver cancer in mice

Qin Wang, Ning Chen, Aijun Yang, Xuenan Wang, Chunna Yu, Zefeng Wei, Boxuan Li, Zewu Li, Zhenzhen Jin; pp 1408-1413 (Pubmed Abstract, PDF)

Observation of therapeutic effect of 125I seed implantation combined with chemotherapy and antiviral therapy on HBV-related liver cancer

Yunjian Zeng, Yingmin Mao, Zili Shi, Yuqi Zhou, Lingfang Zhang; pp 1414-1419 (Pubmed Abstract, PDF)

Establishment and validation of a prognostic model for hepatocellular carcinoma after radical liver resection

Yan Xue, Jianxian Zhang, Yuhuan Bai, Changchun Jing, Zhifeng Zhang, Xiaoyu Sun, Dong Yang, Zhijun Duan; pp 1420-1428 (Pubmed Abstract, PDF)

Clinical value of spectral CT imaging combined with AFP in identifying liver cancer and hepatic focal nodular hyperplasia

Rui Xu, Jing Wang, Xiaoyu Huang, Qiaoying Zhang, Yijing Xie, Lan Pang, Liangcai Bai, Junlin Zhou; pp 1429-1434 (Pubmed Abstract, PDF)

Use of 64-Slice Spiral CT Examinations for Hepatocellular Carcinoma 

Xiangguang Chen, Zhiqi Yang, Junliang Deng; pp 1435-1440 (Pubmed Abstract, PDF)

Overexpressed lncRNA CDKN2B-AS1 is an independent prognostic factor for liver cancer and promotes its proliferation  

Huijie Zhuang, Gang Cao, Changhua Kou, Dechun Li; pp 1441-1448 (Pubmed Abstract, PDF)

COLORECTAL CANCER

Transanal endoscopic microsurgery for radical resection of sigmoid cancer

Dayong Xu, Xiaoyun Liao, Liqiang Hu, Chaowu Chen, Yingbin Hu, Zheng Chen, Ke Yang, Shuangxi Gong; pp 1449-1456 (Pubmed Abstract, PDF)

The efficacy of panitumumab in refractory metastatic colorectal cancer: A meta-analysis

Kun-Feng Duan, Hua Wang; pp 1457-1463 (Pubmed Abstract, PDF)

Silencing of PPMD1 inhibits proliferation of human colon cancer cells via induction of apoptosis and cell cycle arrest

Zhihui Yin, Jian Yi, Tian Nie, Zongliang Yang, Ning Ding, Shot Xian Du, Shan Shan Liu, Tianshu Peng; pp 1464-1469 (Pubmed Abstract, PDF)

Zingiberene inhibits in vitro and in vivo human colon cancer cell growth via autophagy induction, suppression of PI3K/AKT/mTOR Pathway and caspase 2 deactivation

Hai Chen, Xiaocheng Tang, Ting Liu, Liang Jing, Junhui Wu; pp 1470-1475 (Pubmed Abstract, PDF)

MicroRNA-24 regulates the growth and chemosensitivity of the human colorectal cancer cells by targeting RNA-binding protein DND1 

Qiuhuan Zhang, Wenjing Li, Gang Liu, Weizhong Tang; pp 1476-1481 (Pubmed Abstract, PDF)

Curcumin effects on cell proliferation, angiogenesis and metastasis in colorectal cancer

Gizem Calibasi-Kocal, Ahu Pakdemirli, Serdar Bayrak, Nazli Mert Ozupek, Tolga Sever, Yasemin Basbinar, Hullya Ellidokuz, Turkan Yigitbasi; pp 1482-1487 (Pubmed Abstract, PDF)

Dentatin exerts anticancer effects on human colon cancer cell lines via cell cycle arrest, autophagy, inhibition of cell migration and JAK/STAT signalling pathway

Wei Xiong, Jianhua Dong, Shujia Kong; pp 1488-1493 (Pubmed Abstract, PDF)

Assessment of survival and prognostic factors in metastatic colorectal cancer patients treated with first-line bevacizumab-based therapy

Nazim Can Demircan, Faysal Dane, Mehmet Akif Ozturk, Nalan Akgul Babacan, Mehmet Besiroglu, Serap Kaya, Ozlem Ercelep, Eda Tanrikulu, Suleyman Halil, Sinan Koca, Ozkan Alan, Rahip Hasanov, Perran Fulden Yumuk; pp 1494-1500 (Pubmed Abstract, PDF)

Prognostic importance of tumor location and anti-EGFR therapy in patients with K-RAS wild type metastatic colorectal cancer

Mehmet Kucukoner, Even Oztekin, Nadiye Akdeniz, Suat Morkuzu, Halis Yerlikaya, Zuhat Urakci, Muhammed Ali Kaplan, Abdurrahman Isikdogan; pp 1501-1506 (Pubmed Abstract, PDF)

Single nucleotide polymorphism rs2555639 in 15-PGDH and colorectal cancer metastasis 

Suzhen Zhang, Jun Liu, Mudan Yang, Daguang Fan, Jun Gao, Xiaoling Liu, Jingyi Li, Huizhi Feng, Hongxia Lu, Yi Kang; pp 1507-1511 (Pubmed Abstract, PDF)

BREAST CANCER

Physical activity, early first delivery and residence as parameters for breast cancer prevention: an observational study

Vassilis Kouloulias, Kalliopi Platoni, Ioanna Kantzou, Anna Zygogianni, Kyriaki Kyriazi, Andromachi Kougioumtzopoulou, Marios Papaloucas, Christos Papaloucas; pp 1512-1515 (Pubmed Abstract, PDF)

Breast reconstruction with autologous fat combined with platelet rich plasma: fighting between medical novelty and cancer biology

Athanasios Syllaios, Antonios Tsimpoukelis, Ilias Vagios, Eleandros Kyros, Spyridon Davakis; pp 1516-1520 (Pubmed Abstract, PDF)

Management of malignant and borderline phyllodes tumors of the breast: our experience

Stefanos Zervoudis, Grigoris Xepapadakis, Nikos Psarros, Anastasia Bothou, Panagiotis Tsikouras, Georgios Galazios, Panagiota Kontogianni, Maria Papazian, Iordanis Navrozoglou, Georgios Iatrakis, Minas Paschopoulos; pp 1521-1525 (Pubmed Abstract, PDF)

Expression of miR-335 in triple-negative breast cancer and its effect on chemosensitivity

Jie Hao, Minghua Lai, Chunsheng Liu; pp 1526-1531 (Pubmed Abstract, PDF)  

Inhibition of cancer cell growth by Tangeretin flavone in drug-resistant MDA-MB-231 human breast carcinoma cells is facilitated via targeting cell apoptosis, cell cycle phase distribution, phase invasion and activation of numerous Caspases

Shanji Fan, Haifan Xu, Hongguang Liu, Zecheng Hu, Junyan Xiao, Hong Liu; pp 1532-1537 (Pubmed Abstract, PDF)

GYNECOLOGIC CANCERS

The clinical features associated with mutated BRCA1 and 2 genes  in ovarian cancer patients

Paul Kubelac, Catalin Vlad, Ioana Berindan-Neagoe, Alexandru Irimie, Patriciu Achimas-Cadariu; pp 1538-1543 (Pubmed Abstract, PDF)

Comparisons of efficacy and safety between docetaxel + cisplatin and paclitaxel + cisplatin and their effects on serum HE4, CA125 and ROMA indicators in patients with ovarian carcinoma

Liwei Han, Lei Kuang; pp 1544-1548 (Pubmed Abstract, PDF)

High expression of mesothelin in advanced serous ovarian cancer is associated with poor prognosis

Yasar Yildiz, Gokhan Kabadayi, Seyran Yigit, Yuksel Kucukzeybek, Ahmet Alacacioglu, Umut Varol, Halil Taskaynatan, Tarik Salman, Utku Oflazoglu, Murat Akyol, Mustafa Oktay Tarhan; pp 1549-1554 (Pubmed Abstract, PDF)

Inhibition of endometrial carcinoma by Kaempferol is interceded through apoptosis induction, G2/M phase cell cycle arrest, suppression of cell invasion and upregulation of m-TOR/PI3K signalling pathway 

Xia Lei, Jing Guo, Yuan Wang, Jie Cui, Bei Feng, Yani Su, Hong Zhao, Weiwei Yang, Yunfeng Hu; pp 1555-1561 (Pubmed Abstract, PDF)

PANCREATIC CANCER

Ultrasound Combined with CT in Pancreatic Cancer

Lei Liu, Xinweng Huang, Xia Li, Liping Ma, Xiaochun Zhao, Xue Yang; pp 1562-1567 (Pubmed Abstract, PDF)

ERCP combined with tumor markers in differential diagnosis of pancreatic cancer and pseudotumor-like pancreatitis

Bin Luo, Fangyi Peng, Mei Hong, Song Su, Cheng Fang, Xiaoli Yang, Guodong Xia, Bo Li; pp 1568-1573 (Pubmed Abstract, PDF)

Role of miR-489 in the proliferation and apoptosis of pancreatic carcinoma

Maolan Zeng, Yanhua Zhou, Yinxia Zhang, Tiancheng Wang, Jing Wang; pp 1574-1580 (Pubmed Abstract, PDF)

Inhibition of cancer cell growth in gemcitabine-resistant pancreatic carcinoma by mangiferin involves induction of autophagy, endogenous ROS production, cell cycle disruption, mitochondrial mediated apoptosis and suppression of cancer cell migration and invasion

Lei Yu, Min Chen, Rui Zhang, Zhaohui Jin; pp 1581-1586 (Pubmed Abstract, PDF)

GASTRIC CANCER

Efficacy of postoperative imtraperitoneal hyperthermic perfusion chemotherapy with oxaliplatin + 5-Fluorouracil in the treatment of gastric cancer patients with peritoneal carcinomatosis

Kangpeng Yan, Kun Wu, Lan Yan, Lei Liang, Yujun Yuan; pp 1587-1594 (Pubmed Abstract, PDF)

Correlations of gastrointestinal hormones with inflammation and intestinal flora in patients with gastric cancer

Gang Zhou, Jing Yang; pp 1595-1600 (Pubmed Abstract, PDF)

Serum IL-17 levels can be diagnostic for gastric cancer

Mehmet Karabulut, Cigdem Usul Afsar, Murat Serimez, Senem Karabulut; pp 1601-1609 (Pubmed Abstract, PDF)

LUNG CANCER

Radiofrequency ablation of primary non-small cell lung cancer: A retrospective study on 108 patients

Yang Gao, Jun Chen, Jin Zhang, Lei Sun, Yiping Zhuang; pp 1610-1618 (Pubmed Abstract, PDF)

Is stereotactic body radiotherapy an alternative to surgery in early stage non small cell lung cancer?  

Gokhan Yaprak, Ozgur Ozan Seseogullari, Bedriye Dogan Akaslan, Naciye Isik; pp 1619-1625 (Pubmed Abstract, PDF)

Immunohistochemical characteristics of brain metastases and corresponding primary lung cancer

Dora Marinova Marinova, Evgeni Vitkov Mekov, Denitsa Gosheva Dimitrova, Plamen Todorov Titorenkov, Miroslav Martinov Mihailov, Sevdalin Slavov Nachev, Vania Milosheva Youroukova, Dimitar Temelkov Kostadinov, Yanina Georgieva Slavova; pp 1626-1637 (Pubmed Abstract, PDF)

RENAL CELL CARCINOMA

Analysis of efficacy of sorafenib combined with vascular endothelial growth factor inhibitor Avastin in renal cell carcinoma

Qifei Wang, Jie Qin, Xiaoqiang Liu; pp 1638-1643 (Pubmed Abstract, PDF)

Negative prognostic significance of primary cilia, CD8+ tumor infiltrating lymphocytes and PD1+ cells expression in clear cell renal cancer

Aneta Rozsypalova, Blanka Rosova, Alzbeta Filipova, Dimitar Hadzi Nikolov, Renata Chloupkova, Igor Richter, Jan Proks, Roman Zachoval, Radoslav Matter, Bohuslav Melichar, Tomas Buchler, Josef Dvorak; pp 1644-1651 (Pubmed Abstract, PDF)

BLADDER CANCER

Efficacy of bladder perfusion of alternating hydroxycamptothecin and gemcitabine combined with low-dose tuberculin in the treatment of non-muscle invasive bladder cancer after TURBT

Lin Chen, Weifeng Hu, Guohao Li, Yonglian Guo, Zhihua Wan, Jiajun Yu pp 1652-1658 (Pubmed Abstract, PDF)

Prediction of recurrence in non-muscle invasive bladder cancer patients. Do patient characteristics matter? 

Burak Ucpinar, Akif Erbin, Ali Ayranci, Ufuk Caglar, Deniz Alis, Seref Basal, Omer Sarilar, Mehmet Fatih Akbulut; pp 1659-1665 (Pubmed Abstract, PDF)

ESOPHAGEAL CANCER

Correlations of recurrence after radical surgery for esophageal cancer with glucose-lipid metabolism, insulin resistance, inflammation, stress and serum p53 expression

Liang Zheng, Jingting Jiang, Yingting Liu, Xiao Zheng, Changping Wu; pp 1666-1672 (Pubmed Abstract, PDF)

Effects of postoperative enteral nutrition combined with adjuvant radiotherapy on inflammatory response, nutrition, healing and prognosis in patients receiving radical surgery for esophageal carcinoma

Rong Yao, Tiecheng Zhang, Juan Zhang, Yuan Sun, Lijuan Xu, Dahong Zhang, Leilei Zhou; pp 1673-1678 (Pubmed Abstract, PDF)

HEMATOLOGIC MALIGNANCIES

Elevated SOX11 mRNA level correlates with favorable prognosis in mantle cell lymphoma

Jianxia He, Yanfeng Xi, Ning Gao, Enwei Xu, Liwu Xie, Jin Chang, Jie Liu; pp 1679-1685 (Pubmed Abstract, PDF)

In vitro anticancer effects of esculetin against human leukemia cell lines involves apoptotic cell death, autophagy, G0/G1 cell cycle arrest and modulation of Raf/MEK/ERK signalling pathway

Xiaodong Wang, Chunlan Yang, Qian Zhang, Chunjing Wang, Xiaohui Zhou, Xiaoling Zhang, Sixi Liu; pp 1686-1691 (Pubmed Abstract, PDF)

PROSTATE CANCER

miR-146a and miR-152 in prostate cancer and clinicopathological parameters 

Ye Liu, Saiyue Gao, Qingyan Du, Mingming Shao; pp 1692-1699 (Pubmed Abstract, PDF)

HEAD & NECK CANCERS 

SPLUNC1 and MLL3 regulate cancer stem cells in nasopharyngeal carcinoma

Shanyan Bian, Zhiyuan Wang, Yubin Chen, Rui Li; pp 1700-1705 (Pubmed Abstract, PDF)

OSTEOSARCOMA

Inhibitory effect of 5-Fluorouracil on the proliferation of human osteosarcoma cells in vitro 

Kun Jiang, Junhong Zhang, Mingxia Ji, Pengzhou Ge, Qiaoying Lv; pp 1706-1711 (Pubmed Abstract, PDF)

MISCELLANEOUS

The effect of cancer patients’ attachment orientations on their satisfaction of medical care

Eleni Tsilika, Efi Parpa, Anastasia Galanopoulou, Maria Nikoloudi, Antonis Galanos, Kyriaki Mystakidou; pp 1712-1718 (Pubmed Abstract, PDF)

Drug-drug interactions in patients using tyrosine kinase inhibitors: A multicenter restrospective study

Yakup Ergun, Nuriye Yildirim Ozdemir, Serife Toptas, Alican Kurtipek, Tulay Eren, Ozan Yazici, Mehmet Ali Nahit Sendur, Bulent Akinci, Gokhan Ucar, Berna Oksuzoglu, Dogan Uncu; pp 1719-1726 (Pubmed Abstract, PDF)

PTW QUICKCHECKwebline: Daily quality assurance phantom comparison and overall performance

Daniel Nicewonger, Pamela Myers, Daniel Saenz, Neil Kirby, Karl Rasmussen, Niko Papanikolaou, Sotiri Stathakis; pp 1727-1734 (Pubmed Abstract, PDF)

LETTERS TO THE EDITOR

Definition of luminal B HER-2-negative breast cancer should be revisited

Kadri Altundag; p 1735 (Pubmed Abstract, PDF)

CA-125 might be good predictive tumor biomarker for earlier detection of serosal metastases including the ovarian metastasis in high-risk invasive lobular breast cancer

Zohrab Abduyev, Kadri Altundag; p 1735 (Pubmed Abstract, PDF)

HER2 status in residual disease after neoadjuvant treatment might determine sensitivity to trastuzumab emtansine

Kadri Altundag; p 1736 (Pubmed Abstract, PDF)

Topoisomerase IIa deregulation in nasopharyngeal carcinoma

Vasileios Papanikolaou, Aristeidis Chrysovergis, Evangelos Tsiambas, Efthymios Kyrodimos; pp 1736-1737 (Pubmed Abstract, PDF)

Why do triple-negative metaplastic breast cancers tend to metastasize less frequently to lymph nodes ?

Kadri Altundag; p 1737 (Pubmed Abstract, PDF)

Thymidylate synthase expression at metastatic site might be more correlated with response to anti-thymidylate synthase agent in triple negative breast cancers

Kadri Altundag; pp 1737-1738 (Pubmed Abstract, PDF)

The impact of receptor conversion on treatment efficacy and survival in breast cancer patients with brain metastases: Still debatable issue?

Zohrab Abduyev, Kadri Altundag; p 1738 (Pubmed Abstract, PDF)

Author: Andy Athns