SPECIAL ARTICLE

Overview on the current status of virtual high-throughput screening and combinatorial chemistry approaches in multi-target anticancer drug discovery
George D. Geromichalos, Constantinos E. Alifieris, Elena G. Geromichalou, Dimitrios T. Trafalis; pp 764-779  (Pubmed abstrPDF)

REVIEW ARTICLES

Borderline ovarian tumors: A contemporary review of clinicopathological characteristics, diagnostic methods and therapeutic options 
Pinar Solmaz Hasdemir, Tevfik Guvenal; pp 780-786 (Pubmed abstrPDF)

Current therapeutic options targeting bone metastasis in metastatic castration resistant prostate cancer
Charalampos Fragkoulis, Ioannis Gkialas, Georgios Papadopoulos, Konstantinos Ntoumas; pp 787-791 (Pubmed abstrPDF)

Ganoderma Lucidum (Reishi Mushroom) and cancer
Ahmet Unlu, Erdinc Nayir, Onder Kirca, Mustafa Ozdogan; pp 792-798 (Pubmed abstrPDF)

ORIGINAL ARTICLES

BREAST CANCER

Trastuzumab 1-year vs 9-week in early-stage HER2-positive, lymph node negative breast cancer patients
Mehmet Ozen, Mehmet Gunduz, Ozturk Ates, Taner Babacan, Ali R. Sever, Serkan Akin, Yavuz Ozisik, Kadri Altundag; pp 799-808  (Pubmed abstrPDF)

Clinical characteristics and management of a Greek female patient cohort with breast ductal carcinoma in situ
Dimitrios Panousis, Panagiota Kontogianni, Panagiota Ntasiou, Georgia Paraskevakou, Dimitrios Grosomanidis, Konstantinos Chatzopoulos, Efstratia Charitidou, Grigoris Xepapadakis; pp 809-817 (Pubmed abstrPDF)

The role and the potential regulatory pathways of high expression of forkhead box C1 in promoting tumor growth and metastasis of basal-like breast cancer
Hou Dong Zuo, Wei Wu Yao; pp 818-825 (Pubmed abstrPDF)

Correlation of educational status and clinicopathological characteristics of breast cancer: a single center experience
Furkan Sarici, Taner Babacan, Hakan Buyukhatipoglu, Ozan Balakan, Ali R. Sever Neyran Kertmen, Ozan Unlu, Ozturk Ates, Omer Diker, Serkan Akin, Veli Sunar, Yusuf Karakas1, Sahin Lacin, Kadri Altundag; pp 826-831 (Pubmed abstrPDF)

Acceptable adverse outcomes after delayed breast reconstruction using abdominal advancement flap – a 15-year experience
Olivera Kosovac, Nada Santrac, Ivan Markovic, Dusica Gavrilovic, Aleksandar Martinovic, Marko Jevric, Igor Spurnic, Radan Dzodic; pp 832-839 (Pubmed abstrPDF)

The mean platelet volume may predict the development of isolated bone metastases in patients with breast cancer: a retrospective study of the Young Researchers Committee of the Turkish Oncology Group (TOG)
Ozgur Tanriverdi, Serkan Menekse, Fatih Teker, Esin Oktay, Kezban Nur Pilancı, Meral Gunaldi, Muharrem Kocar, Turgut Kacan, Aykut Bahceci, Nilufer Avci, Tulay Akman, Suna Cokmert, Havva Yesil-Cinkir, Mustafa Teoman Yanmaz; pp 840-850 (Pubmed abstr, PDF)

Left laterality is an independent prognostic factor for metastasis in N3 stage breast cancer
Fatih Karatas, Suleyman Sahin, Gokmen U. Erdem, Ozturk Ates, T aner Babacan, Serkan Akin, Ali R. Sever, Yavuz Ozisik, Kadri Altundag; pp 851-858 (Pubmed abstrPDF)

GASTROINTESTINAL CANCERS

The value of calprotectin S100A8/A9 complex as a biomarker in colorectal cancer: A systematic review
Demetrios Moris, Eleftherios Spartalis, Anastasios Angelou, Georgios-Antonios Margonis, Alexandros Papalambros, Athanasios Petrou, Antonios Athanasiou, Dimitrios Schizas, Dimitrios Dimitroulis, Evangelos Felekouras; pp 859-866 (Pubmed abstrPDF)

Cbl-b regulates the sensitivity of cetuximab through ubiquitin-proteasome system in human gastric cancer cells
Ping Yu, Yibo Fan, Xiujuan Qu, Jingdong Zhang, Na Song, Jing Liu, Y unpeng Liu; pp 867-873 (Pubmed abstrPDF)

Prognostic indicators following curative pancreatoduodenectomy for pancreatic carcinoma: A retrospective multivariate analysis of a single centre experience
Athanasios Petrou, Zahir Soonawalla, Michael-Antony Silva, Antonio Manzelli , Demetrios Moris, Patric-Paul Tabet, Peter Friend; pp 874-882 (Pubmed abstrPDF)

Selective cytotoxic effect of Rhododendron luteum extract on human colon and liver cancer cells
Selim Demir, Ibrahim Turan, Yuksel Aliyazicioglu; pp 883-888 (Pubmed abstrPDF)

Bakuchiol inhibits cell proliferation and induces apoptosis and cell cycle arrest in SGC-7901 human gastric cancer cells
Jing Lin, Hui-Jing Yao, Rui-Yun Li; pp 889-894 (Pubmed abstrPDF)

Serum leptin levels may have diagnostic and predictive roles in patients with pancreatic adenocarcinoma treated with gemcitabine-based chemotherapy
Senem Karabulut, Cigdem Usul Afsar, Mehmet Karabulut, Halil Alis, Kayhan Erturk, Sule Karaman, Osman Kones, Elif Bilgin, Faruk Tas; pp 895-902 (Pubmed abstrPDF)

Laparoscopic versus open total gastrectomy for advanced proximal gastric carcinoma: a matched pair analysis
Yi Lu, Baocheng Jiang, Tao Liu; pp 903-908 (Pubmed, abstrPDF)

LIVER CANCER

Metronomic S-1 chemotherapy plus transcatheter arterial chemoembolization (TACE): a promising treatment of hepatocellular carcinoma refractory to TACE
Wukui Huang, Lina You, Shufa Yang, Dengyao Liu, Mo Liu, Hailin Wang, Pingju Wang, Pahaerding Baikere, Peng Gu, Abulajiang Abulikemu, Shaoha Yuan, Xiwen Fan; pp 909-916 (Pubmed abstrPDF)

Inhibitory effects of Silibinin combined with doxorubicin in hepatocellular carcinoma; an in vivo study.
Wei-Guo Li, He-Qun Wang; pp 917-924 (Pubmed abstrPDF)

The pretreatment albumin to globulin ratio, a validated biomarker, predicts prognosis in hepatocellular carcinoma
Jiahe Zhang, Xinhui Liu, Zike Yang, Yingying Chen, Rongcheng Luo; pp 925-934 (Pubmed abstrPDF)

COLORECTAL CANCER

Thymidylate synthase polymorphism in Mexican patients with colon cancer treated with 5-fluorouracil
Clara Patricia Rios-Ibarra, Claudia Janeth Rodriguez-Silva, Yamil Alonso Lopez-Chuken, Rocio Ortiz-Lopez, Elisa Fernandez-Castillo, Claudia Beatriz Del Toro Runzer, Vicente Paul Armenta-Perez, Juan Pablo Flores-Gutierrez, Arturo Quintanilla-Guzman1, Mauricio Salin as-Santander, Juan Francisco Gonzalez-Guerrero, Francisco Bosques-Padilla, Arturo Santos, Herminia Guadalupe Martinez-Rodriguez; pp 935-940 (Pubmed abstrPDF)

Circulating and tissue galectin-1 and galectin-3 in colorectal carcinoma: association with clinicopathological parameters, serum CEA, IL-17 and IL23
Sara Petrovic, Gordana D. Radosavljevic, Jelena Pantic, Ivan Jovanovic, Nikola Jankovic, Nebojsa Arsenijevic; pp 941-949 (Pubmed abstrPDF)

LUNG CANCER

Resveratrol in lung cancer- a systematic review
Yuan Feng, Jihing Zhou, Ying Jiang; pp 950-953 (Pubmed abstrPDF)

Assessment of 64-slice spiral computed tomography with perfusion weighted imaging in the early diagnosis of ground-glass opacity lung cancer
Yinggang Lv, Yurong Jin, Dianguo Xu, Qiaohuan Yan, Guiting Liu, Hui Zhang, Dingling Yuan, Junhui Bao; pp  954-957 (Pubmed abstrPDF)

CNS TUMORS

Survival and prognostic factors in patients with brain metastasis: Single center experience
Kemal Ekici, Oztun Temelli, Mustafa Dikilitas, Ibrahim Halil Dursun, Nihal Bozdag Kaplan, Ersoy Kekilli; pp 958-963 (Pubmed abstrPDF)

Expression profiling of RE1-silencing transcription factor (REST), REST corepressor 1 (RCOR1), and Synapsin 1 (SYN1) genes in human gliomas
Musteyde Yucebas, Sunde Yilmaz Susluer, Hasan Onur Caglar, Tugce Balci, Z. Ozlem Dogan Sigva, Taner Akalin, Nezih Oktar, Tayfun Dalbasti, Cigir Biray Avci, Cumhur Gunduz; pp 964-972 (Pubmed abstrPDF)

OVARIAN CANCER

Expression of CDCP1 and ADAM12 in the ovarian cancer microenvironment
Catalin Vlad, Paul Kubelac, Andrea Onisim, Bogdan Fetica, Annamaria Fulop, Alexandru Irimie, Patriciu Achimaş-Cadariu; pp 973-978 (Pubmed abstrPDF)

HEAD AND NECK CANCER

Weekly cisplatin with radiotherapy for locally advanced head and neck squamous cell carcinoma
Brieuc Sautois, Hélène Schroeder, Marie Martin, Pascal Piret, Pierre Demez, Olivier Bouchain, Eugène Mutijima, Pierre Moreau; pp 979-988 (Pubmed abstrPDF)

THYROID CANCER

High incidence of thyroid cancer among patients with acromegaly
Dimitrios Kaldrymidis, Georgios Papadakis, Georgios Tsakonas, Philippos Kaldrymidis, Theofanis Flaskas, Andreas Seretis, Eleni Pantazi, Ifigenia Kostoglou-Athanassiou, Melpomeni Peppa, Paraskevi Roussou, Evanthia Diamanti-Kandarakis; pp 989-993 (Pubmed abstrPDF)

CANCER EPIDEMIOLOGY

Incidence, mortality, and epidemiological aspects of cancers in Iran; differences with the world data
Zeinab Almasi, Abdollah Mohammadian-Hafshejani, Hamid Salehiniya; pp 994-1004 (Pubmed abstrPDF)

PALLIATIVE CARE

Attachment orientations of Greek cancer patients in palliative care. A validation study of the Experiences in Close Relationships scale (ECR-M16)
Eleni Tsilika, Efi Parpa, Natasa Galanopoulou, Vasiliki Gennimata, Eftychia Mosa, Antonis Galanos, Kyriaki Mystakidou; pp 1005-1012 (Pubmed abstrPDF)

SHORT COMMUNICATION

Bone metastasis in breast cancer is treated by high-dose tamoxifen
George P. Stathopoulos, Dimitrios Trafalis, Maria Kaparelou; pp 1013-1015 (Pubmed abstrPDF)

MISCELLANEOUS

Association of the HOTAIR rs4759314 polymorphism with cancer risk: a meta-analysis
Fang-teng Liu, Liang Zhou, Cheng Qiu, Guang-feng Xia, Pei-qian Zhu, Hong-liang Luo; pp 1016-1023 (Pubmed abstrPDF)

LETTERS TO THE EDITOR

PTEN in laryngeal carcinomas
Vasileios Ragos, Panagiotis P. Fotiades, Evangelos Tsiambas, Dimitrios Peschos; p 1024 (Pubmed abstr, PDF)

Re-affirming the necessity of sending even minor surgical specimens for histopathology: a case of inverted papilloma of the adenoids
Petros V. Vlastarakos, Thomas Georgiadis, Sophia Boutsi, Ilias Konstantopoulos;  p 1025 (Pubmed abstrPDF)

Place of bevacizumab in radiation-induced edema and necrosis
Yasemin Benderli Cihan; p 1026 (Pubmed abstrPDF)

Composite hairy cell leukemia and chronic lymphocytic leukemia.
Alexandra Papoudou-Bai, Amalia Vassou, Georgios Vartholomatos, Evangelos Briasoulis, Panagiotis Kanavaros; pp 1027-1028 (Pubmed abstrPDF)

Topoisomerase IIa expression in laryngeal and oral carcinomas: is it a reliable prognostic molecular marker?
Evangelos Tsiambas, Panagiotis P. Fotiades, Ioannis Kastanioudakis, Vasileios Ragos; pp 1029-1030  (Pubmed abstrPDF)

HISTORY OF ONCOLOGY

Hippocrates (ca 460-370 BC) on nasal cancer
Gregory Tsoucalas, Markos Sgantzos; pp 1031-1034 (Pubmed abstrPDF)