• REVIEW ARTICLES

p53 mutations in oral cavity carcinoma
Vasileios Ragos, Nicholas S. Mastronikolis, Evangelos Tsiambas, Evangelia Baliou, Stylianos N.Mastronikolis, Nikolaos Tsoukalas, Eugenia E Patsouri, Panagiotis P. Fotiades; pp 1569-1572 (Pubmed Abstract, PDF)
Gastrointestinal stromal tumors and synchronous intra-abdominal malignancies: Review of the literature
Alexandros Diamantis, Konstantinos Bouliaris, Grigorios Christodoulidis, Dionysia Vasdeki, Konstantinos Perivoliotis, Konstantinos Tepetes; pp 1573-1579  (Pubmed Abstract, PDF)
Chromosomal instability in oral squamous cell carcinoma
Vasileios S. Papanikolaou, Efthymios Kyrodimos, Evangelos Tsiambas, Evangelos Giotakis, Amanta Psyrri, Vasileios Ragos, Aristeidis Chrysovergis; pp 1580-1582  (Pubmed Abstract, PDF)

ORIGINAL ARTICLES

BREAST CANCER
Combination versus sequential paclitaxel plus gemcitabine as first-line chemotherapy for women with metastatic breast cancer: a prospective randomized phase II study
Bin Shao, Guohong Song, Huiping Li, Lijun Di, Hanfang Jiang, Xu Liang, Ying Yan, Ruyan Zhang, Ran Ran, Jing Wang, Xiaoran Liu, Miaoning You; pp 1583-1590  (Pubmed Abstract, PDF)
Synchronous and metachronous bilateral breast cancer: A long-term experience
lper Ozturk, Gul Alco, Dauren Sarsenov, Serkan Ilgun, Cetin Ordu, Ulkuhan Koksal, Kezban Nur Pilanci,
Zeynep Erdogan, Filiz Izci, Filiz Elbuken, Filiz Agacayak, Fatma Aktepe, Vahit Ozmen; pp 1591-1600  (Pubmed Abstract, PDF)
A study on the relationship between chemotherapy-induced cognitive impairment and age in patients with breast cancer
Zeyu Liu, Xiaorong Han, Chunxiang Tian, Jun Chen, Lei Lei, Qi Liang, Xinlin Lv, Shenli Tang, Ping Ning; pp 1601-1605  (Pubmed Abstract, PDF)
Developing a needs assessment questionnaire for women of reproductive age following breast cancertreatment: a cross-sectional pilot study in a Romanian sample
Florina Pop, Mihaela Iancu, Patriciu Achimas-Cadariu, Alin Bodog, Emil Puscas; pp 1606-1615  (Pubmed Abstract, PDF)
COLORECTAL CANCER
TNF-α-308G/A polymorphism and the risk of colorectal cancer: A systematic review and an updatedmeta-analysis
Zhiwei Miao, Kang Wang, Xiaoyu Wang, Chunyu Zhang, Yan Xu; pp 1616-1624  (Pubmed Abstract, PDF)
Short- and long-term outcomes of laparoscopic complete mesocolic excision in elderly patients with right colon cancer
Jin Li, Lin Yudong, Yong Chen; pp 1625-1632  (Pubmed Abstract, PDF)
MiR-421 inhibited the proliferation and metastasis of colorectal cancer by targeting MTA1
Liang Xue, Dong Yang; pp 1633-1639  (Pubmed Abstract, PDF)
A 20-year single center experience in the surgical treatment of colorectal liver metastasis
Konstantinos Tsalis, Orestis Ioannidis, Angeliki Cheva, Natalia Antigoni Savvala, Nikolaos Antoniou, Styliani Parpoudi, Dimitrios Kyziridis, Dimitrios Tatsis, Dimitrios Konstantaras, Loukiani Kitsikosta, Manousos George Pramateftakis, Efstathios Kotidis, Antonios Avgerinos, Ioannis Mantzoros; pp 1640-1647  (Pubmed Abstract, PDF)

GASTROINTESTINAL CANCERS
Metastasectomy of pancreatic and periampullary adenocarcinoma to solid organ: The current evidence
Mahmud Saedon, Ioannis Maroulis, Adam Brooks, Evangelos Alexiou, Konstantinos Bouliaris, Theofilos Amanatidis, Stylianos Germanos; pp 1648-1654  (Pubmed Abstract, PDF)
Assessing immunological surgical stress markers in patients undergoing digestive surgery for pancreatic, hepatic and gastric tumors
Alexandru Munteanu, Doru Munteanu, Mihaela Iancu, Iulia Lupan, Gabriel Samasca, Cornel Aldea, Teodora Mocan, Cornel Iancu; p 1655 (Pubmed Abstract, PDF)
HEAD & NECK CANCER
An open-label, single-arm phase II clinical study of induction chemotherapy and sequential Nimotuzumab combined with concurrent chemoradiotherapy in N3M0 stage nasopharyngeal carcinoma
Shuai Zhang, Xiaopeng Huang, Liya Zhou, Gang Wu, Jie Lin, Shiping Yang, Junni Chen, Shaomin Lin; pp 1656-1661 (Pubmed Abstract, PDF)
Biological information analysis of differentially expressed genes in oral squamous cell carcinoma tissues in GEO database
Yitong Wang, Hongyi Fan, Liwei Zheng; pp 1662-1670  (Pubmed Abstract, PDF)
Correlation between the expression of miR150 and FOXO4 and the local recurrence and metastasis of nasopharyngeal carcinoma after intensive radiotherapy
Bin Liu, Zhiqiang Tan, Yuling Jiang, Yuehong Chen, Yi Chen, Keji Ling; pp 1671-1678  (Pubmed Abstract, PDF)
Arglabin is a plant sesquiterpene lactone that exerts potent anticancer effects on human oral squamous cancer cells via mitochondrial apoptosis and downregulation of the mTOR/PI3K/Akt signaling pathway to inhibit tumor growth in vivo
Wenpeng He, Renfa Lai, Qiang Lin, Yiman Huang, Lu Wang; pp 1679-1685  (Pubmed Abstract, PDF)
Putative cancer stem cells are present in surgical margins of oral squamous cell carcinoma
Milos Lazarevic, Maja Milosevic, Dijana Trisic, Bosko Toljic, Jelena Simonovic, Nadja Nikolic, Nikola Mikovic, Drago Jelovac, Milan Petrovic, Miroslav Vukadinovic, Jelena Milasin; pp 1686-1692  (Pubmed Abstract, PDF)
LUNG CANCER
Antiproliferative and cytotoxic action of N-(p-coumaroyl) serotonin in lung cancer cells
Michail Mitsis, Georgios Markopoulos, George A. Alexiou, Evrysthenis Vartholomatos, Diamanto Lazari, Entela Hodaj, Dimitrios Nastos, Georgios Lianos, Panagiota Zagorianakou, Vasiliki Galani, Athanasios P. Kyritsis; pp 1693-1698  (Pubmed Abstract, PDF)
Development of novel real-time RT-qPCR methodologies for quantification of the COL11A1 mRNA general and C transcripts and evaluation in non-small cell lung cancer specimens
Tatiana Rizou, Fotis Perlikos, Maria Lagiou, Makrina Karaglani, Sotirios Nikolopoulos, Ioannis Toumpoulis, Christos Kroupis; pp 1699-1710  (Pubmed Abstract, PDF)
HEPATOCELLULAR CARCINOMA
Serum sphingosine 1-phosphate in hepatocellular carcinoma patients is related to HBV infection
Hui Dong, Juan Xiao, Rongping Zhu, Binggang Liu, Mingjun Dong, Diteng Luo, Tian Sun, Qinghua Li, Junfei Jin; pp 1711-1716  (Pubmed Abstract, PDF)
UNC119 promoted cell growth and migration by Wnt/β-catenin signal and TGF-β/EMT signal pathway in hepatocellular carcinoma
Zhi-Hong Liu, You-Fu Zhang, Zhi-Dan Xu; pp 1717-1724  (Pubmed Abstract, PDF)
GYNECOLOGICAL CANCERS
Expression of toll-like receptors in ovarian cancer
Catalin Vlad, Constantin Dina, Paul Kubelac, Diana Vlad, Bogdan Pop, Patriciu Achimas-Cadariu; pp 1725-1731  (Pubmed Abstract, PDF)

Influence of carboplatin on the proliferation and apoptosis of ovarian cancer cells through mTOR/p70s6k signaling pathway
Honghui Zhou, Haibo Zhao, Hui Liu, Xiang Xu, Xiaoli Dong, Enfeng Zhao; pp 1732-1738  (Pubmed Abstract, PDF)
Inhibition of human cervical cancer cell growth by Salviolone is mediated via autophagy induction, cell migration and cell invasion suppression, G2/M cell cycle arrest and downregulation of Nf-kB/m-TOR/PI3K/AKT pathway
Yuening Zhang, Guoxin Li, Chao Ji; pp 1739-1744  (Pubmed Abstract, PDF)
LINC01170 promotes the progression of endometrial carcinoma by activating the AKT pathway
Zhengzheng Zhang, Xiao Liu, Hao Xu, Pan Li, Tian Zeng, Wensheng Du, Xiaoyuan Lu; pp 1745-1752  (Pubmed Abstract, PDF)
Research on correlations of ERCC-1 with proliferation and apoptosis of ovarian cancer cells
Yuqin Zhang, Daoyan Zhang, Hongyan Wang; pp 1753-1795  (Pubmed Abstract, PDF)
PROSTATE CANCER
The expression of PD-L1 in patients with castrate prostate cancer treated with enzalutamide
Igor Richter, Tomas Jirase, Ivana Havlickova, Radmila Curcikova, Vladimír Samal, Josef Dvorak, Jirí Bartos; pp 1796-1802  (Pubmed Abstract, PDF)
Aspirin use improves the biochemical control of prostate cancer in Chinese men
Qiang Hao, Haiying Gong, Huantao Zong, Shaoping Huang, Tao Wang, Yongjian Zhou, Yaoguang Zhang, Yong Zhang; pp 1803-1808  (Pubmed Abstract, PDF)
OSTEOSARCOMA
 [Retracted] Retrospective analysis of the effect of treatment of osteosarcoma complicated by pathological fracture by neoadjuvant chemotherapy combined with limb salvage surgery
Junke Zhu, Tianda He, Zhaoxiang Wei, Yiming Wang; pp 1809-1815  (Pubmed Abstract, PDF)

(This article has been retracted. See the Retraction notice here)
MiR-199b-5p promotes malignant progression of osteosarcoma by regulating HER2
Zi Chen, Guohui Zhao, Yunkun Zhang, Yong Ma, Yin Ding, Nanwei Xu; pp 1816-1824  (Pubmed Abstract, PDF)
HEMATOLOGICAL MALIGNANCIES
Long non-coding RNA H19 promotes proliferation of Hodgkin’s lymphoma via AKT pathway
Yan Wang, Li Wang, Minghua Sui; pp 1825-1831  (Pubmed Abstract, PDF)
Induction of apoptosis in human acute monocytic leukemia (THP-1) cells with NaF and the related mechanisms
Hongmei Jiang, Peng Fang, Guoping Zhang; pp 1832-1839  (Pubmed Abstract, PDF)
CNS TUMORS
Cycloartenol exerts anti-proliferative effects on Glioma U87 cells via induction of cell cycle arrest and p38 MAPK-mediated apoptosis
Huanfu Niu, Xinming Li, Aijun Yang, Zhenzhen Jin, Xuenan Wang, Qin Wang, Chunna Yu, Zefeng Wei, Cuiyun Dou; pp 1840-1845  (Pubmed Abstract, PDF)
MULTIPLE PRIMARY NEOPLASMS
Clinicopathological characteristics of patients with multiple primary neoplasms – a retrospective analysis
Adina Nemes, Nicolae Todor, Viorica Nagy; pp 1846-1854  (Pubmed Abstract, PDF)
GASTROINTESTINAL STROMAL TUMORS
The risk factors about prognosis of 142 GIST patients with recurrence or metastasis: A retrospective study of single centre in Northern China
Yong Li, Bibo Tan, Haifeng Wu, Haisong Xin, Liqiao Fan, Qun Zhao, Zhixue Ma, Yü Liu; pp 1855-1861  (Pubmed Abstract, PDF)

ESOPHAGEAL CANCER
Upregulation of long noncoding RNA ANRIL correlates with tumor progression and poor prognosis in esophageal squamous cell carcinoma
Tinghua Cao, Jiaqing Shen, Wenbin Pan, Chunliang Li, Zhenguo Qiao; pp 1862-1866  (Pubmed Abstract, PDF)
MUSCULOSKELETAL TUMORS
Evaluation of predictive value of 1H MR spectroscopy for response of neoadjuvant chemotherapy in musculoskeletal tumors
Predrag Cirkovic, Jelena Mihailovic, Lejla Paripovic, Vesna Ilic, Dusan Ristic, Igor Djurisic, Aleksandar Djordjevic, Ruzica Maksimovic; pp 1867-1873  (Pubmed Abstract, PDF)
EWING’S SARCOMA
Treatment results of childhood Ewing’s sarcoma of the bone in Serbia
Lejla Paripovic, Vesna Ilic, Marija Pudrlja Slovic, Jelena Bokun, Predrag Cirkovic, Aleksandar Djordjevic, Jelena Sopta, Dragana Vujic, Milan Saric, Marina Nikitovic; pp 1874-1881  (Pubmed Abstract, PDF)
BLADDER CANCER
HMGB1 expression in urothelial carcinoma of the bladder
Dinc Suren, Hulya Tosun Yildirim, Irem Atalay, Alper Sayiner, Mustafa Yildirim, Arsenal Sezgin Alikanoglu, Cem Sezer; pp 1882-1886  (Pubmed Abstract, PDF)
RENAL CELL CARCINOMA
HTERT promoter methylation and single nucleotide polymorphism (-245 T>C) affect renal cell carcinoma behavior in Serbian population
Jovanka Trifunovic, Gordana Basta-Jovanovic, Nadja Nikolic, Jelena Carkic, Ana Marjanovic, Marija Brankovic, Sanja Radojevic Skodric, Mirjana Prvanovic, Aleksandar Jovanovic, Zoran Dzamic, Jelena Milasin; pp 1887-1892  (Pubmed Abstract, PDF)
MISCELLANEOUS
Bone marrow mesenchymal stem cells: improving transgene expression level, transfection efficiency and cell viability
Carlos Gonzalez-Villarreal, Salvador Said-Fernandez, Adolfo Soto-Dominguez, Gerardo Padilla – Rivas, Elsa Garza-Treviño, Humberto Rodriguez Rocha, Herminia Martinez – Rodriguez; pp 1893-1903  (Pubmed Abstract, PDF)
Drug repurposing: mebendazole as effective antitumor agent. Are we seeing the whole story?
Pavle Banovic, Srdjan Stankov, Nenad Vranjes, Ognjen Zurkovic, Ivan Capo, Dusan Lalosevic; pp 1904-1911  (Pubmed Abstract, PDF)
Follicle – stimulating hormone receptors: A comparison of commercially- available monoclonal and polyclonal antibodies as immunohistochemical markers for cancer research
Eduard-Alexandru Bonci, Rares Buiga, Marius Badan, Laura Iuliana Maja, Vlad Alexandru Gata, Ioan Cosmin Lisencu, Alexandru Irimie, Patriciu Achimas-Cadariu, Doina Piciu; pp 1912-1921  (Pubmed Abstract, PDF)

SHORT COMMUNICATION

Neuroendocrine carcinomas of the gallbladder: Lessons learnt from cases at opposite ends of the spectrum
Dimitrios Moris, Diamantis I. Tsilimigras, Jenny Lim, Danielle Camastra, Aditya Nanavati, Stuart J. Knechtle, Andrew S. Barbas; pp 1922-1926  (Pubmed Abstract, PDF)

LETTERS TO THE EDITOR

c kit in oral mucosal melanoma
Evangelos Tsiambas, Nicholas S. Mastronikolis, Vasileios Ragos, Panagiotis P. Fotiades; pp 1927-1928  (Pubmed Abstract, PDF)
Aromatase inhibitors might be more effective when they are given 2-3 months later after the administration of luteinizing hormone-releasing hormone agonists in younger premenopausal breast cancer patients
Kadri Altundag; p 1928  (Pubmed Abstract, PDF)
Bevacizumab, temsirolimus with or without cetuximab: combinational treatment against patients with advanced HNSCC
Dimitrios T. Trafalis, Constantinos Alifieris; p 1928  (Pubmed Abstract, PDF)
HPV DNA methylation in cervical and head and neck carcinomas
Anastasia A. Mortaki, Nicholas S. Mastronikolis, Evangelos Tsiambas, Kalliopi I.Pappa, Vasileios Ragos; p 1929  (Pubmed Abstract, PDF)
Retesting HER2 status in axillary node metastases has important potential as a guide to subsequent therapy after pathologic complete eradication of cytologically proven hormone receptor positive and HER2-negative primary breast cancer following neoadjuvant treatment
Kadri Altundag; p 1930  (Pubmed Abstract, PDF)
Chromosomal instability mapping in meningioma
Dimitrios K. Roukas, Vasileios Ragos, Nicholas S. Mastronikolis, Evangelos Tsiambas; p 1931  (Pubmed Abstract, PDF)
Role of mTOR signaling pathway proteins and proteins influencing mTOR pathwayin resistance to radiotherapy in prostate cancer
Yasemin Benderli Cihan; pp 1931-1932  (Pubmed Abstract, PDF)

HISTORY OF ONCOLOGY

Le “canceur des fumeurs” in 19th century: the contribution of the French surgeon Étienne-Frédéric Bouisson (1813-1884)
Marianna Karamanou, Gregory Tsoucalas, George Zografos, Manolis Vavuranakis, George Androutsos; pp 1933-1938  (Pubmed Abstract, PDF)