REVIEW ARTICLES

Carbon nanotubes: An alternative for platinum-based drugs delivery systems
Daniel Salas-Trevino, Odila Saucedo-Cardenas, Maria de Jesus Loera-Arias, Edgar Gerardo De Casas-Ortiz, Humberto Rodriguez-Rocha, Aracely Garcia-Garcia, Roberto Montes-de-Oca-Luna, Adolfo Soto-Dominguez; pp 541-549 (Pubmed Abstract, PDF)

The foundation of personalized medicine is the establishment of biobanks and their standardization
Liliana Policiuc, Mihail Buse, Diana Gulei, Alina Andreea Zimta, Cornelia Braicu, Alexandra Iulia Irimie,Ioana Berindan-Neagoe; pp 550-560 (Pubmed Abstract, PDF)

Photodynamic combinational therapy in cancer treatment
Qianyu Zhang, Libo Li; pp 561-567 (Pubmed Abstract, PDF)

Adjuvant chemotherapy for high-risk stage II and stage III colon cancer: timing of initiation and optimal duration
Jan Paolo M. Cruz, Chris George C. Pales, Kwang Min Kim, Young Wan Kim; pp 568-573 (Pubmed Abstract, PDF)

ORIGINAL ARTICLES

COLORECTAL CANCER

Anticancer activity of safranal against colon carcinoma is due to induction of apoptosis and G2/M cell cycle arrest mediated by suppression of mTOR/PI3K/Akt pathway

Yibing Zhang, Yong Zhao, Jianyou Guo, Haifeng Cui, Sha Liu; pp 574-578 (Pubmed Abstract, PDF)

MiR-503 promotes the migration and invasion of colorectal cancer cells by regulating PDCD4
Lihua Li, Xiaolian Zhang, Zengxing Yi, Xiaofang Liang, Weihua Yin, Shaoyuan Li; pp 579-586 (Pubmed Abstract, PDF)

Antitumor effects of emodin in CACO-2 human colon carcinoma cells are mediated via apoptosis, cell cycle arrest and downregulation of PI3K/AKT signalling pathway

Qianzhang Ma, Yuanquan Ding, Zhenqi Wu, Yan Li; pp 587-591 (Pubmed Abstract, PDF)

Ultrasound/CT combined with serum CEA/CA19.9 in the diagnosis and prognosis of rectal cancer

Beibei Zhang, Zhenzhong Sun, Min Song, Suqiao Ma, Yujing Tian, Qingfeng Kong; pp 592-597 (Pubmed Abstract, PDF)

KISS1 and KISS1R expression in primary and metastatic colorectal cancer
Spyridon Matthaiou, Ioannis D. Kostakis, Stylianos Kykalos, Nikolaos Machairas, Eleftherios Spartalis, Evangelia Ntikoudi, Maria Lambropoulou, Anastasios Karayiannakis; pp 598-603 (Pubmed Abstract, PDF)

HEPATOCELLULAR CARCINOMA

miR-218 suppresses the growth of hepatocellular carcinoma by inhibiting the expression of protooncogene Bmi-1

Jing Wu, Zhi-mao Jiang, Yong Xie, Xuan-qiu He, Xiao-hua Lin, Jin-ling Hu, Yan-zhong Peng; pp 604-610 (Pubmed Abstract, PDF)

Selection of treatment modalities for hepatocellular carcinoma at stages T1 and T2: A preliminary analysis based on the Surveillance, Epidemiology, and End Results registry database

Bing Han, Hui Yao, Lichun Shao, Xiaozhong Guo, Lei Han, Fernando Gomes Romeiro, Andrea Mancuso, Xingshun Qi; pp 611-621 (Pubmed Abstract, PDF)

Blood sugar level affects the recurrence of hepatocellular carcinoma after laparoscopic surgery: a retrospective study
Weiwei Yu, Yan Wang, Guangjun Liao; pp 622-628 (Pubmed Abstract, PDF)

Comparison of the effects of postoperative prophylactic trans-catheter arterial chemoembolization (TACE) and transhepatic arterial infusion (TAI) after hepatectomy for primary liver cancer

Jing Chen, Yue Zhang, Huihua Cai, Yu Yang, Yun fei Duan; pp 629-634 (Pubmed Abstract, PDF)

LUNG CANCER

Lupeol triterpene exhibits potent antitumor effects in A427 human lung carcinoma cells via mitochondrial mediated apoptosis, ROS generation, loss of mitochondrial membrane potential and downregulation of m-TOR/PI3K/AKT signalling pathway

Wei He, Xiang Li, Shuyue Xia; pp 635-640 (Pubmed Abstract, PDF)

Effect of genistein on apoptosis of lung adenocarcinoma A549 cells and expression of apoptosis factors

Lin Zhang, Xinxin Ma, Youhong Dong; pp 641-646 (Pubmed Abstract, PDF)

Clinical impact of gastric acid suppressing medication on the effectiveness of tyrosine kinase inhibitors in lung cancer patients

Marcos Nieves Sedano, Jose Manuel Caro Teller, Carmen Garcia Munoz, Delia Fernandez Redondo, Santiago Ponce Aix, Miguel Menendez Orenga, Jose Miguel Ferrari Piquero; pp 647-653 (Pubmed Abstract, PDF)

An observational study of apatinib mesylate in treating advanced non-small cell lung cancer with unknown driving gene(s)

Shaoshuang Fan, Yuhuan Zou, Yifeng Wang, Fang Fang, Wenguang Song; pp 654-658 (Pubmed Abstract, PDF)

GASTRIC CANCER

A study on the roles of Helicobacter pylori in bile reflux gastritis and gastric cancer

Haige Huang, Jun Tian, Xin Xu, Qiong Liang, Xusen Huang, Jiaming Lu, Yongliang Yao; pp 659-664 (Pubmed Abstract, PDF)

Correlation of COX-2 and MMP-13 expressions with gastric cancer and their effects on prognosis

Jianli Ren, Jian Liu, Xin Sui; pp 665-671 (Pubmed Abstract, PDF)

Perioperative blood transfusion is one of the factors that affect the prognosis of gastric cancer

Dazhou Xu, Xinjian Fang, Yi Li, Zhimei Zhang, Qiuling Li; pp 672-677 (Pubmed Abstract, PDF)

Effects of probiotics combined with enteral nutrition on immune function and inflammatory response in postoperative patients with gastric cancer

Honghu Xie, Qicheng Lu, Haitao Wang, Xianbo Zhu, Zhong Guan; pp 678-683 (Pubmed Abstract, PDF)

BREAST CANCER

Promoter hypermethylation of p16, BRCA1 and RASSF1A genes in triple-negative breast cancer patients from Serbia

Zoran Kozomara, Gordana Supic, Ana Krivokuca, Zvonko Magic, Radan Dzodic, Zorka Milovanovic, Mirjana Brankovic-Magic; pp 684-691 (Pubmed Abstract, PDF)

A miRNAs profile evolution of triple negative breast cancer cells in the presence of a possible adjuvant therapy and senescence inducer

Raduly Lajos, Cornelia Braicu, Ancuta Jurj, Segiu Chira, Roxana Cojocneanu-Petric, Valentina Pileczki, Ioana Berindan-Neagoe; pp 692-705 (Pubmed Abstract, PDF)

Factors influencing participation in breast cancer opportunistic screening in Belgrade, Serbia

Ana Jovicevic, Svetlana Ristic, Vera Mandic, Dragana Jovicevic, Tatjana Rajovic, Suzana Stojanovic-Rundic, Tatjana Pekmezovic; pp 706-712 (Pubmed Abstract, PDF)

The expression of ANXA3 and its relationship with the occurrence and development of breast cancer

Tao Zhou, Liang Liu, Li Yang, Yingchao Ju, Chunxiao Li; pp 713-719 (Pubmed Abstract, PDF)

The potential pathway of FOXC1 high expression in regulating the proliferation, migration, cell cycle and epithelial-mesenchymal transition of basal-like breast cancer and in vivo imaging
Houdong Zuo, Qiong Yang; pp 720-728 (Pubmed Abstract, PDF)

OSTEOSARCOMA

Marrubenol inhibits osteosarcoma cancer cell growth by inducing autophagic cell death and inhibiting cancer cell migration and invasion

Yu Zhang, Renshi Ma, Shihuan Cheng, Guishan Gu; pp 729-734 (Pubmed Abstract, PDF)

Pelargonidin induces antitumor effects in human osteosarcoma cells via autophagy induction, loss of mitochondrial membrane potential, G2/M cell cycle arrest and downregulation of PI3K/AKT signalling pathway

Yonggang Chen, Shuanke Wang, Bin Geng, Zhigang Yi; pp 735-740 (Pubmed Abstract, PDF)

HEMATOLOGICAL MALIGNANCIES

Carnosic acid regulates cell proliferation and invasion in chronic myeloid leukemia cancer cells via suppressing microRNA-708

Deliang Liu, Biao Wang, Yuandong Zhu, Feng Yan, Weimin Dong; pp 741-746 (Pubmed Abstract, PDF)

Anticancer effects of Carvone in myeloma cells is mediated through the inhibition of p38 MAPK signalling pathway, apoptosis induction and inhibition of cell invasion

Xiaoqing Ding, Haiyan Chen; pp 747-751 (Pubmed Abstract, PDF)

GYNECOLOGICAL MALIGNANCIES

Antiproliferative activity of Farnesol in HeLa cervical cancer cells is mediated via apoptosis induction, loss of mitochondrial membrane potential (ΛΨm) and PI3K/Akt signalling pathway

Yao-Lei Wang, Hai-Fang Liu, Xiao-Jin Shi, Yi Wang; pp 752-757 (Pubmed Abstract, PDF)

Analysis of clinical effects of neoadjuvant chemotherapy in advanced epithelial ovarian cancer

Yanhua Jiang, Wenfeng He, Heng Yang, Zhenwen Su, Lixin Sun; pp 758-762 (Pubmed Abstract, PDF)

Anticancer effects of Rosmarinic acid in OVCAR-3 ovarian cancer cells are mediated via induction of apoptosis, suppression of cell migration and modulation of lncRNA MALAT-1 expression

Yan Zhang, Min Hu, Liu Liu, Xiao-Ling Cheng, Jing Cai, Jian Zhou, Tao Wang; pp 763-768 (Pubmed Abstract, PDF)

Correlations of p53 expression with transvaginal color Doppler ultrasound findings of cervical cancer after radiotherapy

Pingping Wang, Wenqing Sun, Longxia Wang, Jie Gao, Jie Zhang, Ping He; pp 769-775 (Pubmed Abstract, PDF)

BLADDER CANCER

LncRNA-SNHG7 regulates proliferation, apoptosis and invasion of bladder cancer cells

Xintai Zhong, Zhaolin Long, Shihao Wu, Meiling Xiao, Weilie Hu; pp 776-781 (Pubmed Abstract, PDF)

Effects of human enhancer of filamentation 1 (HEF1) gene on the proliferation, invasion and metastasis of bladder cancer cells

Zhiling Tang; pp 782-786 (Pubmed Abstract, PDF)

RENAL CELL CARCINOMA

MiR-384 represses tumorigenesis by regulating CDK6 and predicts prognosis of clear cell renal cell carcinoma

Lihua Guo, Dayu Wang, Zhiping Zhang; pp 787-794 (Pubmed Abstract, PDF)

Galangin induced antitumor effects in human kidney tumor cells mediated via mitochondrial mediated apoptosis, inhibition of cell migration and invasion and targeting PI3K/AKT/mTOR signalling pathway
Yun Zhu, Qiu Rao, Xinhua Zhang, Xiaojun Zhou; pp 795-799 (Pubmed Abstract, PDF)

CNS TUMORS

Chitosan-capped gold nanoparticles impair radioresistant glioblastoma stem-like cells

Mihaela Aldea, Monica Potara, Olga Soritau, Ioan Stefan Florian, Adrian Florea, Timea Nagy-Simon, Valentina Pileczki, Ioana Brie, Dana Maniu, Gabriel Kacso; pp 800-813 (Pubmed Abstract, PDF)

ESOPHAGEAL CANCER

Effects of MiR-210 on proliferation, apoptosis and invasion abilities of esophageal cancer cells

Zhiwen Cheng, Haitao Geng, Yufeng Cheng, Ningxia Dong, Fangling Ning, Zeshun Yu, Jinbo Jian, Shaoshui Chen; pp 814-819 (Pubmed Abstract, PDF)

GASTROINTESTINAL STROMAL TUMORS

A comparative study of treatment of gastrointestinal stromal tumors with laparoscopic surgery: a retrospective study

Bin He, Su Yan, Rui Li, Hongqing Qiu, Jianchen Tu; pp 820-825 (Pubmed Abstract, PDF)

PTERYGIUM

Deregulation of p53/survivin apoptotic markers correlated to PTEN expression in pterygium neoplastic cells

Kallirroi Konstantopoulou, Evangelos Tsiambas, Evangelia Baliou, Andreas C. Lazaris, Nikolaos Kavantzas, Andreas Karameris, Panagiotis P. Fotiades, Ioannis Asproudis, Vasileios Ragos, George Vilaras, Efstratios Patsouris, Kallirroi Konstantopoulou, Evangelos Tsiambas, Evangelia Baliou, Andreas C. Lazaris, Nikolaos Kavantzas, Andreas Karameris, Panagiotis P. Fotiades, Ioannis Asproudis, Vasileios Ragos, George Vilaras, Efstratios Patsouris; pp 826-831 (Pubmed Abstract, PDF)

SPECIAL ARTICLE

Cancer wars: reflections of a medical oncologist from a visit to Moscow in 1987

Spyros Retsas; pp 832-834 (Pubmed Abstract, PDF)

LETTERS TO THE EDITOR

Is it rational to extend the duration of preventive endocrine treatment in hormone receptor positive ductal carcinoma in situ?

Kadri Altundag; p 835 (Pubmed Abstract, PDF)

PD-L1 in oral squamous cell carcinoma

Evangelos Tsiambas; p 835 (Pubmed Abstract, PDF)

Are bilateral and unilateral interval breast cancers different?

Kadri Altundag; p 836 (Pubmed Abstract, PDF)

The role of radiotherapy following mastectomy and reconstruction

Yasemin Benderli Cihan; pp 837-838 (Pubmed Abstract, PDF)

Are intramammary lymph node metastases significant in the staging of breast cancer?

Kadri Altundag; p 838 (Pubmed Abstract, PDF)

Importance of telomere length and telomerase activity in radiosensitivity

Yasemin Benderli Cihan; 838-839 (Pubmed Abstract, PDF)

CORRESPONDENCE

Surgical training in Greece: is there a feasible and efficient plan to overcome the Crisis?

Demetrios Moris, Georgia – Sofia Karachaliou, Diamantis I. Tsilimigras, Evangelos Felekouras;pp 840-841 (Pubmed Abstract, PDF)

HISTORY OF ONCOLOGY

The distinguished Greek born, French ophthalmologist Photinos Panas (1832-1903) and his views on ocular cancer

Konstantinos Laios, Marianna Karamanou, Efstathia Lagiou, Konstantinos Ioannidis, Despoina Pavlopoulou, Vicky Konofaou, George Androutsos; pp 842-845 (Pubmed Abstract, PDF)