REVIEW ARTICLE 

Caspase complex in laryngeal squamous cell carcinoma 

Aristeidis Chrysovergis, Vasileios S. Papanikolaou, Evangelos Tsiambas, Dimitrios Kikidis, Panagiotis Maragoudakis, Vasileios Ragos, Efthymios Kyrodimos; pp 1-4 (Pubmed Abstract, PDF) 

SPECIAL ARTICLES 

Changes in the incidence of breast cancer due to the use of radioactive materials for warfare or nuclear and environmental accidents over the last 60 years in Europe and Asia 

Antonios Koutras, Ioannis Tsilikis, Athanasios Syllaios, Ifigeneia Zouliati, Prokopis-Andreas Zotos, Georgios Kalinterakis, Athina Karagkouni, Athanasios Chaidoulis, Pinelopi Papachatzopoulou; pp 5-10  (Pubmed Abstract, PDF

LungCARD – Report on worldwide research and clinical practices related to lung cancer 

Radmila Jankovic, Helena J. Goncalves, Milena Cavic, Carla Clemente, Michael Lind, Alexis Murillo Carrasco, Selama Nadi , Meriem Khyatti, Tumininu Adebambo, Dilshod Egamberdiev; pp 11-19 (Pubmed Abstract, PDF)

ORIGINAL ARTICLES 

BREAST CANCER 

Receptor discordances in locally advanced breast cancer after neoadjuvant chemotherapy and their effects on survival 

Deniz Tural, Mustafa Karaca, Alisan Zirtiloglu, Bekir M. Hacioglu, Mehmet AN Sendur, Ahmet Ozet; pp 20-25 (Pubmed Abstract, PDF)

Correlations of DKK1 with incidence and prognosis of breast cancer 

Wenkai Sun, Jian Shang, Jianguo Zhang, Shixuan Chen, Min Hao; pp 26-32 (Pubmed Abstract, PDF)

The diagnostic value of MRI multi-parameter combination for breast lesions with ring enhancement 

Mingfeng Niu, Xingwen Huang, Qiang Yin; pp 33-39 (Pubmed Abstract, PDF)

Correlations of breast cancer FHIT gene with the incidence and prognosis of breast cancer 

Yu Fu, Xiaojun Shan, Wenqing Song, Kai Xu, Chunyu Jiao, Qibing Zhang; pp 40-47 (Pubmed Abstract, PDF

Radioactive seed localization and wire guided localization in breast cancer: A systematic review and meta-analysis 

Gui-lin Wang, Panagiotis Tsikouras, Huai-quan Zuo, Ming-quan Huang, Lin Peng, Anastasia Bothou, Stefanos Zervoudis, Alexander Tobias Teichmann; pp 48-60 (Pubmed Abstract, PDF

Effect of miR-200c on the proliferation, migration and invasion of breast cancer cells and relevant mechanisms 

Xiaoqing Yuan, Juan Liu, Xinhua Ye; pp 61-67 (Pubmed Abstract, PDF)

COLORECTAL CANCER 

First-line treatment choices of Turkish medical oncologists in metastatic colorectal cancer: A survey study

Ismail Beypinar, Murat Araz, Mukremin Uysal, Suayib Yalcin; pp 68-76 (Pubmed Abstract, PDF

Analyses of predictive factors for pathological complete remission in neoadjuvant therapy for locally advanced rectal cancer 

Jun Yang, Xin Ling, Wen Tang, Duanmin Hu, Haiyun Zhou, Guojian Yin; pp 77-83 (Pubmed Abstract, PDF)

A study on the correlations of MRP-1 expression with the pathogenesis and prognosis of colorectal cancer 

Jing Yang, Peng Song, Gang Zhou; pp 84-90 (Pubmed Abstract, PDF

The effect of omentin-1 on the proliferation and apoptosis of colon cancer stem cells and the potential mechanism 

Hua Ji, Lijuan Wan, Qunhui Zhang, Mingwei Chen, Xiaotong Zhao; pp  91-98 (Pubmed Abstract, PDF)

High expression of Plnc RNA-1 promotes the progression of colorectal cancer 

Baolian Song, Yuping Jia; pp 99-105 (Pubmed Abstract, PDF)

Antiproliferative effects of propofol and lidocaine on the colon adenocarcinoma microenvironment 

Tiberiu Tat, Ancuta Jurj, Cristina Selicean, Sergiu Pasca, Daniela Ionescu; pp 106-115 (Pubmed Abstract, PDF

Effect of AMPK/Akt/mTOR pathway on cytokine-induced killer cells immunotherapy on colorectal cancer cells 

Jianfeng Shi, Jinfeng Wu, Haibin Ni, Xiaobo Zhan, Lu Zhang, Zhe Zhang; pp 116-122 (Pubmed Abstract, PDF

Comparison of safety of loop ileostomy and loop transverse colostomy for low-lying rectal cancer patients undergoing anterior resection: A retrospective, single institute, propensity score-matched study 

Xiyu Sun, Huiqiao Han, Huizhong Qiu, Bin Wu, Guole Lin, Beizhan Niu, Jiaolin Zhou, Junyang Lu, Lai Xu, Guannan Zhang, Yi Xiao; pp 123-129 (Pubmed Abstract, PDF


Angustifoline inhibits human colon cancer cell growth by inducing autophagy along with mitochondrial-mediated apoptosis, suppression of cell invasion and migration and stimulating G2/M cell cycle arrest 

Zheyu Ding, Qingbo Chen, Bin Xiong, Yingli Cun, Hongbo Wang, Mingyao Xu; pp 130-135 (Pubmed Abstract, PDF

A retrospective analysis on first-line bevacizumab, cetuximab, and panitumumab-containing regimens in patients with RAS-wild metastatic colorectal cancer: A Collaborative Study by Turkish Oncology Group (TOG) 

Serkan Degirmencioglu, Ozgur Tanriverdi, Serkan Menekse, Mutlu Dogan, Bekir Hacıoglu, Esin Oktay, Dilek Erdem, Erkan Arpaci, Basak Oyan Uluc, Serdar Turhal, Merve Yilmaz, Kezban Nur Pilanci, Abdullah Sakin, Murat Araz, Suna Cokmert, Ozlem Ozdemir, Erdem Sen, Erdinc Nayir; pp 136-142 (Pubmed Abstract, PDF)

HEPATOCELLULAR CARCINOMA 

Hepatic arterial infusion in liver tumors of unknown, uncertain or unusual primary: single-center experience 

Bohuslav Melichar, Josef Dvorak, Katerina Kamaradova, Antonín Krajina, Hana Studentova; pp 143-149 (Pubmed Abstract, PDF)

Comparison of 10 prognostic staging systems in patients with advanced hepatocellular carcinoma 

Lei Wang, Yutao Xian, Zhengqiang Yang; pp 150-157 (Pubmed Abstract, PDF)

Microwaves as modulators of membrane stability parameters during hepatic cancer 

Guo Cunli, Bi Yumei, Zhang Lei, Xu Yi, Wang Qiucheng;pp 158-162 (Pubmed Abstract, PDF

Analysis of efficacy and safety of TACE in combination with RFA and MWA in the treatment of middle and large primary hepatic carcinoma 

Peng Yuan, Zhigang Zhang, Jinacg Kuai; pp 163-170 (Pubmed Abstract, PDF

Short-term efficacy of oral low-dose Tegafur chemotherapy after transarterial chemoembolization in primary hepatic carcinoma 

Diemian Liang, Bo Yang; pp 171-177 (Pubmed Abstract, PDF

MiR-5692a promotes proliferation and inhibits apoptosis by targeting HOXD8 in hepatocellular carcinoma 

Shijie Sun, Ning Wang, Ziwen Sun, Xuefeng Wang, Hongwei Cui; pp  178-186 (Pubmed Abstract, PDF)

GASTRIC CANCER 

Correlation of COX-2 and MMP-13 expressions with gastric cancer and their effects on prognosis
Jianli Ren, Jian Liu, Xin Sui; pp 187-193 (Pubmed Abstract, PDF

Effect of early oral feeding on gastrointestinal function recovery in postoperative gastric cancer patients: a prospective study 

Lin Gao, Zhenguo Zhao, Liying Zhang, Guoyi Shao; pp 194-200 (Pubmed Abstract, PDF

Neoadjuvant chemotherapy brings more survival benefits than postoperative chemotherapy for resectable gastric cancer: a Meta-analysis of randomized controlled trials 

Yu Hu, Dongyan Hu, Wenhui Li, Xuejun Yu; pp 201-214 (Pubmed Abstract, PDF)

Investigation on correlations of serum IL-26 with diagnosis and staging of gastric cancer 

Tianhui Xue, Jing Yang, Peng Song, Gang Zhou; pp 215-220 (Pubmed Abstract, PDF

In vitro and in vivo antitumor activity of neochlorogenic acid in human gastric carcinoma cells are complemented with ROS generation, loss of mitochondrial membrane potential and apoptosis induction 

Wei Fang, Yuntao Ma, Juan Wang, Xiaojun Yang, Yuanhui Gu, Yiping Li; pp 221-226 (Pubmed Abstract, PDF)

PROSTATE CANCER 

Effects of diabetes mellitus and Metformin administration on prostate cancer detection at biopsy among Chinese men: a case-control study 

Meng-Bo Hu, Pei-De Bai, Yi-Shuo Wu, Li-Min Zhang, Wen-Hui Zhu, Ji-Meng Hu, Tian Yang, Hao-Wen Jiang, Qiang Ding; pp 227-232 (Pubmed Abstract, PDF

The assessment of knowledge and attitudes of men in Serbia about prostate cancer and possibilities for its early detection and treatment in 2011: a cross-sectional study 

Jelena Petrovic, Miodrag Acimovic, Ana Jovicevic, Dragutin Rafailovic, Ivana Petrovic, Zoran Dzamic, Tomislav Pejcic, Jovan Hadzi-Djokic; pp 233-238 (Pubmed Abstract, PDF 

Comparison of radical prostatectomy versus conservative treatment in localized prostate cancer: systematic review and meta-analysis
Zijian Tian; Xin Wang; Pengjie Wu; Tao Shi; Ming Liu; pp 239-248 (Pubmed Abstract, PDF)

MicroRNA-140 inhibits proliferation and promotes apoptosis and cell cycle arrest of prostate cancer via degrading SOX4 

Yifan Liu, Fangfang Li, Dehui Lai, Qingling Xie, Yufei Yin, Minlong Yang, Zexuan Su; pp 249-255 (Pubmed Abstract, PDF)

LUNG CANCER 

Tumor characteristics, expressions of ERCC1, Bax, p53, IGF1R, Bcl2, Bcl2/Bax and prognostic factors for overall survival in patients with lung carcinoid 

Marta Velinovic, Radmila Jankovic, Dragana Jovanovic, Vesna Skodric Trifunovic, Dusica Gavrilovic, Jelena Stojsic, Milena Cavic; pp  256-266 (Pubmed Abstract, PDF)

Percutaneous computed tomography-guided localization of pulmonary nodules with hook wire prior to video-assisted thoracoscopic surgery 

Stamo Manouvelou, Eftychia Mosa, Maria Tolia, Nikolaos Tsoukalas, Michail Nikolaou, Georgios Nikolaou, Apostolos Dountsis, Efthymios Andriotis, Konstantinos Vasilikos, George Kyrgias; pp 267-272 (Pubmed Abstract, PDF)

MicroRNA-122-5p promotes the development of non-small cell lung cancer via downregulating p53 and activating PI3K-AKT pathway 

Xiaowu Fan, Xiaowei Wu; pp 273-279 (Pubmed Abstract, PDF)

GYNECOLOGIC CANCER 

Gentiopicroside exerts convincing antitumor effects in human ovarian carcinoma cells (SKOV3) by inducing cell cycle arrest, mitochondrial mediated apoptosis and inhibition of cell migration 

Xiaohao Li, Chenglin Yang, Hao Shen; pp  280-284  (Pubmed Abstract, PDF)

Suppression of in vitro and in vivo human ovarian cancer growth by isoacteoside is mediated via sub-G1 cell cycle arrest, ROS generation, and modulation of AKT/PI3K/m-TOR signalling pathway 

Xili Yang, Fei Guo, Qingmei Peng, Yang Liu, Bin Yang; pp 285-290 (Pubmed Abstract, PDF)

Clinicopathological factors influencing the prognosis of cervical cancer 

Junfeng Gai, Xiaoyan Wang, Yun Meng, Zengling Xu, Mingjie Kou, Yongli Liu; pp  291-295 (Pubmed Abstract, PDF)

RENAL CANCER 

Inhibition of kidney cancer cell growth by Mulberroside-A is mediated via mitochondrial mediated apoptosis, inhibition of cell migration and invasion and targeting EGFR signalling pathway 

Chaoyang Duan, Jin Han, Chongyu Zhang, Kunyi Wu, Yan Lin; pp 296-300 (Pubmed Abstract, PDF)

Cyclin D1 and p57 expression in relation to clinicopathological characteristics and overall survival in patients with renal cell carcinoma 

Dragana Latic, Snezana Pejic, Slavisa Savic, Zlatibor Loncar, Ivan M. Nikolic, Gorana Nikolic, Ivan Pavlovic, Sanja Radojevic-Skodric; pp  301-309 (Pubmed Abstract, PDF)

Sorghumol triterpene inhibits the growth of circulating renal cancer cells by promoting cell apoptosis, G2/M cell cycle arrest and downregulating m-TOR/PI3K/AKT signalling pathway 

Hao Li, Chao Dan, Xiaofang Gong, Wenjing Zeng, Qisheng Yao, Yong Yang, Xiaoxin Gong, Li Wang, Congbo Chen, Li Huang; pp 310-314 (Pubmed Abstract, PDF)

HEAD AND NECK CANCER 

Clinical significance of miRNA-195 expression in patients with laryngeal carcinoma
Detao Ding, Zhiling Qi; pp 315-322 (Pubmed Abstract, PDF)

Linalool monoterpene exerts potent antitumor effects in OECM 1 human oral cancer cells by inducing sub-G1 cell cycle arrest, loss of mitochondrial membrane potential and inhibition of PI3K/ AKT biochemical pathway 

Weijuan Pan, Guohua Zhang; pp 323-328 (Pubmed Abstract, PDF)

BLADDER CANCER 

PI3K/AKT pathway genetic alterations and dysregulation of expression in bladder cancer 

Stefanos Kachrilas, Athanasios Dellis, Athanasios Papatsoris, Socratis Avgeris, Dimitra Anastasiou, Ariana Gavriil, Maria Horti, Sofia Tseleni-Balafouta, Konstantinos Livadas, Dimitrios J. Stravopodis, Gerassimos Alivizatos, Gerassimos E. Voutsinas, Charalambos Deliveliotis; pp 329-337 (Pubmed Abstract, PDF)

MELANOMA

The influence of nano-TiO2 on metabolic activity, cytotoxicity and ABCB5 mRNA expression in WM- 266-4 human metastatic melanoma cell line 

Bogdan Zdravkovic, Tanja Prunk Zdravkovic, Marko Zdravkovic, Borut Strukelj, Polonca Ferk; pp 338-346 (Pubmed Abstract, PDF)

MISCELLANEOUS 

Potential of utilization of albumin as a delivery module in cancer model
Da-Nian Tang, Zhe Jin, Jin-Sheng Li, Anshoo Malhotra; pp 347-353  (Pubmed Abstract, PDF)

Association between HOTAIR polymorphisms and cancer risk: a meta-analysis based on twenty-one case-control studies 

Tian Xu, Yu Zhou, Yun Zhang, Chong Yang, Hongji Yang, Shikai Zhu; pp 354-367 (Pubmed Abstract, PDF)

NEUROENDOCRINE TUMORS 

Role of everolimus in the treatment of advanced neuroendocrine tumor: a meta-analysis of randomized trials 

Ze-Guo Zhuo, Yun-Ke Zhu, Han-Yu Deng, Gang Li, Jun Luo, Gu-Ha Alai, Yi-Dan Lin; pp 368-373 (Pubmed Abstract, PDF)

HEMATOLOGIC MALIGNANCIES 

Apatinib enhances chemosensitivity of acute myeloid leukemia hl60 cells to cytarabine by inducing apoptosis 

Qing Pan, Jiuhe Wang, Xianqin Jiang, Enqin Yang, Lin Dong, Kebin Gu; pp  374-381  (Pubmed Abstract, PDF)

THYROID CANCER 

Association between Tsukuba elasticity scores 4 and 5 on elastography and Bethesda undetermined cytology on US-guided FNA with 27-G needle, verified by histopathology: a cut-o point of 20 mm of diameter designated for thyroid nodules 

Demet Sengul, Ilker Sengul; pp 382-390 (Pubmed Abstract, PDF)

MESOTHELIOMA 

Ten-year experience with peritoneal mesothelioma 

Dimitrios Kyziridis, Christos Hristakis, Apostolos Kalakonas, Dimitrios Vaikos, Nikolaos Pallas, Christina Karamveri, Vasileios Kyriakopoulos, Antonios-Apostolos Tentes; pp 391-396 (Pubmed Abstract, PDF)

GLIOBLASTOMA 

Combination treatment for glioblastoma with temozolomide, DFMO and radiation 

George A. Alexiou, Evrysthenis Vartholomatos, Konstantinos I. Tsamis, Evangelia Peponi, George Markopoulos, Vasiliki A.Papathanasopoulou, Ifigeneia Tasiou, Vassilios Ragos, Periklis Tsekeris, Athanasios P. Kyritsis, Vasiliki Galani; pp 397-404 (Pubmed Abstract, PDF)

LETTERS TO THE EDITOR 

Does Oxaliplatin increase radiotherapy-induced lung injury?
Yasemin Benderli Cihan; p 405 (Pubmed Abstract, PDF)

Adjuvant chemotherapy might show benefit in luminal B breast cancer patients with isolated locoregional recurrence 

Kadri Altundag; p 405 (Pubmed Abstract, PDF)

Telomerase activity in laryngeal squamous cell carcinoma 

Aristeidis Chrysovergis, Vasileios S. Papanikolaou, Evangelos Tsiambas, Efthymios Kyrodimos; pp 406-407 (Pubmed Abstract, PDF)

Trastuzumab-emtansine might affect the survival outcome by reversing increased platelet-to- lymphocyte ratio in HER2-positive metastatic breast cancer patients 

Kadri Altundag; p 407 (Pubmed Abstract, PDF)

FDG PET targets dominantly stromal cells 

Ismini Mainta, Dimitris Maintas; p 408 (Pubmed Abstract, PDF)

Multidisciplinary management of complicated small bowel adenocarcinoma on the ground of Crohn’s disease 

Ioannis Ntanasis-Stathopoulos, Maria Gavriatopoulou, Diamantis I. Tsilimigras, Theodosios Theodosopoulos; p 408 (Pubmed Abstract, PDF)

Breast cancer survivors might get more benefit if musical therapy is added to exercise
Kadri Altundag; p 409 (Pubmed Abstract, PDF)

HISTORY OF ONCOLOGY 

Oncologic conceptions in the work of the surgeon Guy de Chauliac (c. 1300-1368) 

Gregory Tsoucalas, Marianna Karamanou, Konstantinos Laios, Konstantinos Markatos, George Androutsos; pp 410-414 (Pubmed Abstract, PDF)

Author: Andy Athns