REVIEW ARTICLES

Histone deacetylase inhibitors as a new anticancer option: How far can we go with expectations?

Anna Garmpi, Nikolaos Garmpis, Christos Damaskos, Serena Valsami, Eleftherios Spartalis, Anastasios Lavaris, Nikolaos Patelis, Georgios-Antonios Margonis, Konstantinos G. Apostolou, Michael Spartalis, Nikolaos Andreatos, Evangelos Diamantis, Konstantinos Tsivelekas, Marilita M. Moschos, Afroditi Nonni, Gerasimos Tsourouflis, Konstantinos Markatos, Efstathios A. Antoniou, Konstantinos Kontzoglou, Nikolaos Nikiteas, Dimitrios Dimitroulis; pp 846-861 (Pubmed Abstract, PDF)

BRCA genes: BRCA 1 and BRCA 2
Umut Varol, Yuksel Kucukzeybek, Ahmet Alacacioglu, Isil Somali, Zekiye Altun, Safiye Aktas, Mustafa Oktay Tarhan; pp 862-866 (Pubmed Abstract, PDF)

Goblet cell carcinoid of the appendix. Review of the literature a propos of a rare case of endometrial metastases

Milan Zegarac, Srdjan Nikolic, Daniela Kolarevic, Milan Kocic, Igor Djurisic, Zorka Inic, Marko Buta, Ana Cvetkovic, Ivan Markovic; pp 867-871 (Pubmed Abstract, PDF)

Literature review on the feasibility of laparoscopic partial nephrectomy for renal cancer during pregnancy: a propos of a case
Bogdan Petrut, Maximilian Hogea, Tiberiu Tat, Mihail Buse, Vlad Schitcu, Zeno Sparchez; pp 872-876 (Pubmed Abstract, PDF)

ORIGINAL ARTICLES

BREAST CANCER
Is adjuvant chemotherapy necessary for Luminal A-like breast cancer?
Halil Taskaynatan, Yuksel Kucukzeybek, Ahmet Alacacioglu, Yasar Yildiz, Tarik Salman, Utku Oflazoglu, Umut Varol, Betul Bolat Kucukzeybek, Murat Kemal Atahan, Mustafa Oktay Tarhan; pp 877-882 (Pubmed Abstract, PDF)
Treatment outcome in patients with breast conserving surgery after neoadjuvant therapy for breast carcinoma – a single institution  experience
Aleksandar Martinovic, Nada Santrac, Ivana Bozovic-Spasojevic, Srdjan Nikolic, Ivan Markovic, Branko Lukic, Dusica Gavrilovic, Miroslav Granic, Radan Dzodic; pp 883-890 (Pubmed Abstract, PDF)
Identification of key candidate genes, pathways and related prognostic values in ER-negative/HER2-negative breast cancer by bioinformatics analysis
Nan Shao, Kaitao Yuan, Yunjian Zhang, Tuck Yun Cheang, Jie Li, Ying Lin; pp 891-901 (Pubmed Abstract, PDF)
The influence of PTEN protein expression on disease outcome in premenopausal hormone receptor positive early breast cancer patients treated with adjuvant ovarian ablation: a long-term follow-up
Tamara Ursulovic, Zorka Milovanovic, Natasa Medic-Milijic, Dusica Gavrilovic, Vesna Plesinac-Karapandzic, Snezana Susnjar; pp 902-909 (Pubmed Abstract, PDF)
Myocardial damage on SPECT imaging among patients treated with radiotherapy for left-sided breast cancer: Systematic review with meta-analysis and narrative synthesis
Stella Pak, Ahmed A. Hawash, Juan Linares, Damian Valencia, Andrew Kilgore, Victor Valencia, John-Philip Markovic; pp 910-918 (Pubmed Abstract, PDF)
Qualitative diagnosis of benign breast lesions and breast carcinoma with elastographic ultrasonic imaging
Youdong Han, Chunmei Zhang, Juanjuan Pang, Shaochun Wang, Lei Zhang, Kailong Li, Bing Song; pp 919-924 (Pubmed Abstract, PDF)

COLORECTAL CANCER

Worst outcomes according to RAS mutation variants: an analysis in patients with metastatic colorectal adenocarcinoma

Pedro L.S. Usón Jr, Diogo D.G. Bugano, Fernando Moura, Ricardo S.Carvalho, Fernando C. Maluf; pp 925-935 (Pubmed Abstract, PDF)

Polymorphism RAD51 172G > T in Serbian patients with colorectal cancer
Jelena Petrovic-Sunderic, Sandra Dragicevic, Mina Krnjajic, Momcilo Ristanovic, Aleksandra Nikolic, Zoran Krivokapic; pp 936-940 (Pubmed Abstract, PDF)

Involvement of general practitioners in colorectal cancer voluntary screening campaign: a mixed-methods study

Rositsa Dimova, Rumyana Stoyanova, Miglena Tarnovska; pp 941-949 (Pubmed Abstract, PDF)

Short- and long-term outcomes of laparoscopic complete mesocolic excision for transverse colon cancer

Meng Yue, Yue Wang, Zhen-Hua Kang, Xu Wang, Lei Wang; pp 950-957 (Pubmed Abstract, PDF)

HEPATOCELLULAR CARCINOMA

Diabetes mellitus may worsen the prognosis in hepatocellular carcinoma
patients undergoing curative microwave ablation

Shi-rong Liu, Ren Chao, Ping Liang, Xiao-ling Yu, Zhi-gang Cheng, Zhi-yu Han; pp 958-964 (Pubmed Abstract, PDF)

Antitumor effects of beta-amyrin in Hep-G2 liver carcinoma cells are mediated via apoptosis induction, cell cycle disruption and activation of JNK and P38 signalling pathways

Song Wen, Danlin Gu, Hui Zeng; pp 965-970 (Pubmed Abstract, PDF)

Short- and long-term outcomes of laparoscopic hepatectomy in elderly patients with hepatocellular carcinoma
Wenjie Wang, Zhenyu Huang, Bencheng Guo, Shihai Liu, Wenjing Xiao, Jun Liang; pp 971-978 (Pubmed Abstract, PDF)

Value of MRI apparent diffusion coefficient for assessment of response to sorafenib in hepatocellular carcinoma

Osman Kostek, Erdem Yilmaz, Muhammet Bekir Hacıoglu, Bulent Erdogan, Hilmi Kodaz, Esma Turkmen Bekmez, Ilhan Hacıbekiroglu, Sernaz Uzunoglu, Nermin Tuncbilek, Irfan Cicin; pp 979-984 (Pubmed Abstract, PDF)

CT combined with tumor markers in the diagnosis and prognosis of hepatocellular carcinoma

Xingwen Huang, Jianlin Li, Fuzheng Wang, Mingda Hao; pp 985-991 (Pubmed Abstract, PDF)

GASTRIC CANCER

Clinical significance of neoangiogenesis and index of proliferation in the signet ring type of gastric adenocarcinoma

Dragos Stojanovic, Sanja M. Milenkovic, Nebojsa Mitrovic, Dejan Stevanovic, Damir Jasarovic, Stevan Matic, Zorana Vukasinovic Bokun, Snezana Jancic; pp 992-1003 (Pubmed Abstract, PDF)

Short- and long-term outcomes of conversion in laparoscopic gastrectomy for gastric cancer

Zhenhao Ding, Li Jiang, Ke Zhang, Ronghai Huang; pp 1004-1012 (Pubmed Abstract, PDF)

Identification modules of gastric cancer based on protein-protein interaction networks and gene expression data

Wei Cui, Zhenfang Gu, Haiying Liu, Chunmei Zhang, Jie Liu; pp 1013-1019 (Pubmed Abstract, PDF)

A five split-field three dimensional conformal technique versus an anterior-posterior on in postoperative radiotherapy for gastric carcinoma: a multicenter comparative study using quality of life measurements as well as clinical and dosimetric parameters

Anna Zygogianni, Andreas Fotineas, Kalliopi Platoni, George Patatoukas, Maria Dilvoi, Christos Antypas, Christina Armpilia, Nikolaos Arkadopoulos, Adamandia Psyrri, George Koukourakis, John Kouvaris, Zoi Liakouli, George Kyrgias, Maria-Aggeliki Kalogeridi, Maria Tolia, Nikolaos Trogkanis, Andromachi Kougioumtzopoulou, Eyfrosini Kypraiou, Nikolaos Kelekis, Vassilis Kouloulias; pp 1020-1028 (Pubmed Abstract, PDF)

THYROID CANCER

RANKL, OPG, TRAIL, KRas, and c-Fos expression in relation to central lymph node metastases in papillary thyroid carcinoma

Maria V. Deligiorgi, Helen Mahaira, Christos Eftychiadis, Georgia Kafiri, Georgia Georgiou, George Theodoropoulos, Manousos M.
Konstadoulakis, Eleni Zografos, George C. Zografos; pp 1029-1040 (Pubmed Abstract, PDF)

Features of lymph node metastasis of papillary thyroid carcinoma in ultrasonography and CT and the significance of their combination in the diagnosis and prognosis of lymph node metastasis

Qiaoqiao Wei, Daozhu Wu, Hongxia Luo, Xiaohua Wang, Rong Zhang, Yongfang Liu; pp 1041-1048 (Pubmed Abstract, PDF)

Multifocality as independent prognostic factor in papillary thyroid cancer – A multivariate analysis

Ivan Markovic, Merima Goran, Nikola Besic, Marko Buta, Igor Djurisic, Dejan Stojiljkovic, Milan Zegarac, Gordana Pupic, Zorka Inic, Radan Dzodic; pp 1049-1054 (Pubmed Abstract, PDF)

PROSTATE CANCER

Royleanone diterpenoid exhibits potent anticancer effects in LNCaP human prostate carcinoma cells by inducing mitochondrial mediated apoptosis, cell cycle arrest, suppression of cell migration and downregulation of mTOR/PI3K/AKT signalling pathway

Xiaoming Wu, Yi He, Gaoyue Zhang, Jianhui Wu, Yansong Hou, Yanqin Gu, Hao Chen; pp 1055-1060 (Pubmed Abstract, PDF)

Interobserver agreement in prostate cancer detection using multiparametric MRI

Cristian Popita, Anca-Raluca Popita, Adina Andrei, Adriana Rusu, Bogdan Fetica, Bogdan Petrut, Tudor Eliade Ciuleanu, Ioan Coman; pp 1061-1069 (Pubmed Abstract, PDF)

LUNG CANCER

Biweekly cisplatin and gemcitabine with two different doses in non small cell lung cancer patients: A retrospective single-center experience

Ender Dogan, Mahmut Ucar, Teoman Sakalar, Sumeyra Derin, Oktay Bozkurt, Mevlude Inanc, Metin Ozkan; pp 1070-1076 (Pubmed Abstract, PDF)

Circulating tumor cells predict prognosis following second-line AZD 9291 treatment in EGFR-T790M mutant non-small cell lung cancer patients
Baohong Yang, Dejie Zheng, Υanyan Zeng, Aiying Qin, Jianfeng Gao, Guohua Yu; pp 1077-1081 (Pubmed Abstract, PDF)

ENDOMETRIAL CANCER

Knockdown of mutated ARID1A inhibited endometrial cancer cell proliferation and stimulated cell apoptosis

Yang Ye, Bao Wei, Xi Xiaowei; pp 1082-1091 (Pubmed Abstract, PDF)

Tanshinone l exhibits anticancer effects in human endometrial carcinoma HEC-1-A cells via mitochondrial mediated apoptosis, cell cycle arrest and inhibition of JAK/STAT signalling pathway

Qian Li, Jing Zhang, Ying Liang, Weihong Mu, Xiaolin Hou, Xu Ma, Qinying Cao; pp 1092-1096 (Pubmed Abstract, PDF)

RENAL CELL CARCINOMA

Correlation of VEGF and EGFR in peripheral blood with clinical stage and pathological grade of renal cell carcinoma and analysis of prognosis

Chenlong Chu, Caifeng Lu, Zhaohui Zhang, Chenhui Zhao, Meizhen Gu, Anqing Yang, Binbin Ma, Zhixiang Xin, Renjie Cui, Min Wu, Tao Huang, Wenlong Zhou; pp 1097-1102 (Pubmed Abstract, PDF)

Immunohistochemical expression of proliferative markers in renal cell
carcinoma

Jovanka Trifunovic, Mirjana Prvanovic, Aleksandar Jovanovic, Zoran Dzamic, Miodrag Lazic, Momcilo Ristanovic, Sanja Radojevic-Skodric, Gordana Basta-Jovanovic; pp 1103-1110 (Pubmed Abstract, PDF)

HEAD & NECK CANCER

Clinical study of cetuximab combined with radical radiotherapy in the treatment of locally advanced sinonasal squamous cell carcinoma
Xianben Qiu, Jie Yang; pp 1111-1117 (Pubmed Abstract, PDF)

The management of locally advanced head and neck squamous and basal cell carcinomas

Pantelis Diamantopoulos, Parthena Deskoulidi, Ioannis Dalianoudis, Christos Farazi Chongouki, Nikolaos Maltzaris, Dimitrios Agorogiannis, Dimitrios Filippou, Maria Kotrotsiou, Panagiotis Skandalakis, Spiros Stavrianos; pp 1118-1124 (Pubmed Abstract, PDF)

GERM CELL TUMORS

N-cadherin expression in primary and metastatic testicular germ cell tumors
Berna Aytac Vuruskan, Hulya Ozturk Nazlioglu, Hakan Vuruskan; pp 1125-1129 (Pubmed Abstract, PDF)

BLADDER CANCER

Association between GPX1 and SOD2 genetic polymorphisms and overall survival in patients with metastatic urothelial bladder cancer: a single-center study in Serbia

Predrag Nikic, Dejan Dragicevic, Ana Savic-Radojevic, Marija Pljesa-Ercegovac, Vesna Coric, Djurdja Jovanovic, Uros Bumbasirevic,Tatjana Pekmezovic, Tatjana Simic, Zoran Dzamic, Marija Matic; pp 1130-1135 (Pubmed Abstract, PDF)

GLIOMA

Gene expression profile analysis of U251 glioma cells with shRNA-mediated SOX9 knockdown

Dongni Ren, Chen Yang, Nan Liu, Zhen Wang, Xin Wang, Mark Johnson, Wenshi Wang, Pengxing Zhang, Hongwei Yang, Hui Liu, Yingduan Cheng, Liang Wang, Yanyang Tu; pp 1136-1148 (Pubmed Abstract, PDF)

GASTROINTESTINAL STROMAL TUMORS

Analyzing the molecular mechanism of the tissue specificity of gastrointestinal stromal tumors by using bioinformatics approaches
Ning Ma, Huaen Xu, Yun Zhou, MingYue Liu, JianWei Zhou, ChaoJie Wang; pp 1149-1155 (Pubmed Abstract, PDF)

MEDULLOBLASTOMA

Management and treatment of children with medulloblastoma in Serbia, a middle-income country

Jelena Bokun, Danica Grujicic, Milica Skender-Gazibara, Lejla Paripovic, Tatjana Pekmezovic, Darija Kisic-Tepavcevic, Vesna Ilic,
Savo Raicevic, Dragana Stanic, Ivana Miskovic, Milan Saric, Marina Nikitovic; pp 1156-1162 (Pubmed Abstract, PDF)

MELANOMA

Picrocrocin exhibits growth inhibitory effects against SK-MEL-2 human malignant melanoma cells by targeting JAK/STAT5 signaling pathway, cell cycle arrest and mitochondrial mediated apoptosis
Lingling Yu, Jing Li, Ming Xiao; pp 1163-1168 (Pubmed Abstract, PDF)

MENINGIOMA

Intracranial meningioma: Experience with stereotactic radiotherapy
Omer Yazici, Yasemin Guzle Adas, Esra Kekilli, Tamer Calikoglu, Muzaffer Bedri Altundag, Ali Riza Ucer, Gulcin Ertas, Sema Durmus Duzgun, Kenan Ozbagi, Atilla Demirkasimoglu, Erdal Demir, Bora Aslan, Bektas Kaya; pp 1169-1173 (Pubmed Abstract, PDF)

RETINOBLASTOMA

Methyl eugenol induces potent anticancer effects in RB355 human retinoblastoma cells by inducing autophagy, cell cycle arrest and inhibition of PI3K/mTOR/Akt signalling pathway

Li Yin, Zhaohui Sun, Qian Ren, Xian Su, Delong Zhang; pp 1174-1178 (Pubmed Abstract, PDF)

HEMATOLOGICAL MALIGNANCIES

Different expressions of miR-125b and SOX30 in malignant lymphomas and their significance
Chengzhi Zhan, Tao Wang, Hua You, Cheng Si; pp 1179-1184 (Pubmed Abstract, PDF)

MISCELLANEOUS

Positive expression of chemokine (C-C Motif) ligand 18 and prognosis in cancer: A meta-analysis

Hui Huang, Jing Li, Wen-jia Hu, Mei-hui Chen, Sha-sha Chen, Chen Chen, Hai-qing Luo, Ke-yuan Zhou, Xin-guang Liu, Xiang-yong Li; pp 1185-1194 (Pubmed Abstract, PDF)

Frequency of XRCC1 Exon 9 G>A gene polymorphism in Saudi Arabian population: A comparative study with worldwide ethnic groups
Shafiul Haque; pp 1195-1199 (Pubmed Abstract, PDF)

LETTERS TO THE EDITOR

Do concurrent targeted treatments and radiotherapy cause additional acute side effects

Yasemin Benderli Cihan; p 1200 (Pubmed Abstract, PDF)

Should addition of five years of ovarian suppression to tamoxifen be “must” for hormone receptor positive and HER-2 positive breast cancer under the age of 35?

Kadri Altundag; p 1201 (Pubmed Abstract, PDF)

Does trainee involvement in Ivor Lewis esophagectomy impact outcomes in any way: A question looking for an answer
Dimitrios Schizas, Diamantis I. Tsilimigras, Demetrios Moris, Theodore Liakakos; pp 1201-1202 (Pubmed Abstract, PDF)

Reducing dietary argininine restriction may decrease the metastatic potential of primary breast cancer

Kadri Altundag; pp 1202-1203 (Pubmed Abstract, PDF)

Irreversible electroporation for Stage III locally advanced pancreatic cancer: Single-center experience

John Spiliotis, Nikolaos Kopanakis, Alexis Terras, Elias Efstathiou; pp
1203-1204 (Pubmed Abstract, PDF)

Which nut fights stage III colon cancer better?
Kadri Altundag; p 1204 (Pubmed Abstract, PDF)

Is exercise a ‘must’ for breast cancer survivors: Yes, it is!

Kadri Altundag; pp 1204-1205 (Pubmed Abstract, PDF)

HISTORY OF ONCOLOGY

Heart cancer in the writings of the anatomo-clinical School members
Marianna Karamanou, Georgia Papastavrou, Konstantinos Toutouzas, Kostas Markatos, George Androutsos; pp 1206-1209 (Pubmed Abstract, PDF)